Firestormm
Senior Member
- Messages
- 5,055
- Location
- Cornwall England
Apologies that it has taken me so long to type up the transcript to the presentation made by Newton at the Action For ME Annual General Meeting back at the end of November in 2012.
I referred originally to it here and we discussed it a bit on that thread. Newton covers all the research currently being conducted as well as past research and clinical treatment for - in the main - autonomic nervous system dysfunction, in her own inimitable style.
From the presentation:
There was much in the talk that I found interesting about POTS for example and in relation to the muslce-gym where muscle cells are exercised in the lab to help determine and confirm the irregularities in our muscle function - as well as helping to determine viable treatments.
The sound quality - especially for the Q&A - was not the best and so I've had to summarise some of the questions asked for example because of a lack of microphones.
Usual caveats apply, namely that I can't guarantee the accuracy of my transcript, although you have links to the video and to the slides in order to compare.
Hope you enjoy as much as I have. You can of course follow developments in Newcastle from their Facebook page - though it's not wholly interactive but good for news in my 'umble opine.
Fire
I referred originally to it here and we discussed it a bit on that thread. Newton covers all the research currently being conducted as well as past research and clinical treatment for - in the main - autonomic nervous system dysfunction, in her own inimitable style.
From the presentation:
Slide 24 – Looking forward:
MRC Medical Research Council
o Understanding the pathogenesis of autonomic dysfunction in CFS and its relationship with cognitive impairment
o Identifying the biological fingerprints of fatigue
o Understanding Muscle Dysfunction in ME/CFS – developing a drug Pre-Testing System
o A case controlled study exploring the qualitative experience of sleep, the roles of sleep architecture and patters of salivary cortisol in ME/CFS
Julia Newton:
"Looking forward, I am very pleased to say that in the recent round of applications for the CFS call from the MRC, in Newcastle we were very successful in securing £900,000 of the £1.5 million, ‘pot’.
So now we are in a very nice position to begin to understand what causes the autonomic dysfunction that seems to be so prevalent in CFS and how it relates to cognitive impairment. And what we are now able to do is do all of those investigations that I have highlighted, plus many more, in the same people – so we will be able to look in a whole-systems-way at what is the underpinning problems in people with CFS/ME.
We’ve also obtained a project where I am the co-investigator, and Dr Wan Ng is the principal investigator – he is an immunologist – to look at trying to identify an immunological biomarker for fatigue; and we’ve made an application to ME Research UK to try and allow us to straddle these two applications and make the very most out of both of them by maximising the samples we can take."
There was much in the talk that I found interesting about POTS for example and in relation to the muslce-gym where muscle cells are exercised in the lab to help determine and confirm the irregularities in our muscle function - as well as helping to determine viable treatments.
The sound quality - especially for the Q&A - was not the best and so I've had to summarise some of the questions asked for example because of a lack of microphones.
Usual caveats apply, namely that I can't guarantee the accuracy of my transcript, although you have links to the video and to the slides in order to compare.
Hope you enjoy as much as I have. You can of course follow developments in Newcastle from their Facebook page - though it's not wholly interactive but good for news in my 'umble opine.
Fire