pomegranate supplement MAY have increased my stamina a little


Moderator Resource
Southern California
The operative word is may. I got the idea of trying pomegranate from this thread by @Niklas where he mentioned pomegranate as a possible source of Urolithin A. What is Urolithin A I asked (myself)? And then read a bit about it and how it can increase endurance and help repair mitochondria, a match made in heaven for ME/CFS it would seem. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial | Geriatrics | JAMA Network Open | JAMA Network

And pomegranate supplements are cheap. So I've been taking a pomegranate supp about 10 weeks now (started it around November 7) - I noticed at Christmas time that a few times when I ordinarily would have crashed without fail the next day (one involving a 3-hour car ride and other activities in one day), I didn't crash the next day. Though I have crashed since starting it, but I think overall I do have more stamina.

My body has worked like clockwork for many years - do x amount of exertion and a crash is guaranteed the next day. Many things have helped me feel better in between crashes, but nothing has increased my energy envelope or stamina until, apparently, the pomegranate.

I started with this supplement and then switched to this from Swanson's, which I think is a better product. I take 2 a day, one with breakfast and one with lunch. I happened to mention to one of my sons around Christmas that I seemed to have more stamina, could do a bit more without crashing, and he said he had noticed the same thing - (I'm so fortunate my kids have never questioned the reality of ME/CFS!)

Anyways, pomegranate is the only thing I can think of that I'm doing differently. I'd have to get more scientific about testing my limits which I don't want to do right now, but sometime I will deliberately try pushing myself beyond what feels safe - just a bit - to see how I do.


You reminded me that I got a little boost when I last tried a pomegranate extract product. I ran out and switched to another polyphenol product that I wanted to use up, which I didn't feel anything from. I am going to try the pomegranate again.


Senior Member
Good story - I like pomegranate, very rich in polyphenols and I have read that it can help with promoting the good bacteria in the gut. Also, a big fan of Siberian Ginseng and Jiaogulan. I feel that the Siberian Ginseng gives me a more solid energy.


Senior Member
A while ago I experimented with an ellagic acid supplement (ellagic acid is thought to be one of the main beneficial polyphenol components of pomegranate).

I found ellagic acid, even in small doses, would cause imaginative and strange dreams (that were actually quite hard going, because of their weirdness). This occurred even if I took ellagic acid in the morning.

I bought this concentrated pomegranate extract (90% ellagic acid) from purebulk.com.

Even small doses like 50 mg of this ellagic power produced the imaginative dreams.

A study says human ellagic acid doses are in the range of 30–850 mg daily.

In terms of the amount of ellagic acid in pomegranate juice, I found different estimates:

Pomegranate juice has 103 mg of ellagic acid per litre. 1
180 ml of pomegranate juice contains 25 mg of ellagic acid. 1
Pomegranate juice has 2.1–7.7 mg of ellagic acid per litre. 1

One study found that humans taking pomegranate juice for 3 years had a reduction in their arterial plaque, possibly due to the potent antioxidant effects of pomegranate polyphenols like ellagic acid.

vision blue

Senior Member
All interesting. Besides liking it, Pomegranate (the actual fruit was one of the very few things my body (both digestive track and mast cells) ) could tolerate during the time when i coukd barely eat anything. At that tine, i looked into what else was in the same class chemically/genetically as the pomegranate hoping to expand my tiny pool of acceptable foods. Was surprised to read the fruuit was in a class of its own and dis not have anything considered a close relative

Ive tbought pomegranates were one of the good things about winter (along with bloid oranges which i can tolerate even tbo cannot tolerate regular oranges) altho they do make my teeth hurt so ive cut down sone. I imagine theres not much active ingredient in a half a pom.

Look forward to getting updates


Senior Member
I found ellagic acid, even in small doses, would cause imaginative and strange dreams (that were actually quite hard going, because of their weirdness). This occurred even if I took ellagic acid in the morning.

I also noticed this when I began taking a pomegranate supplement. Most of my dreams are nightmares and now they are way more vivid which is not pleasant at all. Would be interesting to know if pomegranate increases or decreases sleep quality.

This study shows that pomegranate juice decreases melatonin so it isn't probably a good idea to take it before bed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977483/
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Senior Member
United Kingdom
The main reason I am taking this is to lift akkermansia species - which feed on a variety of polyphenol rich foods - sadly almost all of these are high in oxalates and now I form kidney stones super easily partly because of the valtrex crystalleria I can't eat them. I did try but the kidney stones became acute so I won't be doing that again.

Pomegrenate at 1000mg a day has the extra benefit of being just like Chanca Piedra (the stone breaker) as it prevents supersaturation of calcium oxalate in the kidney urine and dilates the ureter and bladder to allow stones to pass more easily. It also raises the PH of the urine, which is good if your PH isn't a 7 I guess.

Anyway I have been taking it for a few days and noticed it does seem to give me a bit of an energy boost but I am taking other things as well so it's impossible to know if it's that.

On the plus side these polyphenol rich extracts are amazing for gut health if like me you can't tolerate say dark chocolate with a variety of other oxalate foods due to kidney stones. I am also allergic to birch tree pollen which rules out many foods.

Life Extension do pomegrenate they also do apple and blueberry in case anyone is interested. UK people can buy from dolphinfitness for a discounted price.