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Plastic can harm your health - Breakspear Fatigue panel showing that there were plastic particles pr

Anyone any thoughts on this?

https://breakspearmedical.com/wp-content/uploads/2017/06/Issue42SpringSummer2017.pdf Page

Case study:ME/CFS patient’s health restored
This is a condensed version of Dr Daud Mohamed’s case study of a patient whose health was restored by treating him for an illness that was caused by environmental factors. (Full version available upon request.)

Mr TH is 45 years old and attended Breakspear Medical in 2015 for environmental and integrative treatment of his medical condition.

His main symptoms were fatigue and brain fog.

Determining the causes of fatigue is always difficult and there are many labels we can apply to it, such as CFS, ME, myalgia etc. In determining the root cause of low energy production, we need to look at pollutant load and its effect on mitochondrial function (energy production), as well as possible viral infection.

Pollutant exposure in the home and workplace and in

the atmosphere is being increasingly recognised as a causative factor in many conditions.

Here we examine if pollutant load makes the patient more susceptible to viral infection and whether simple steps can be taken to minimise the risk of a recurring fatigue. Fatigue in this case is not “normal” fatigue whereby energy is promptly restored with rest. Pathological fatigue, as experienced in ME/CFS, may combine exhaustion, weakness, heaviness, general malaise, light- headedness and sleepiness that can become overwhelming.


Mr TH was a fit and very active person who cycled on a regular basis and did this as a hobby. On a windy Sunday morning in March 2009, he led a group of cyclists and cycled for about 70 miles. He was fine until the following Friday when he became very unwell and was off sick for a week and became bedridden. Since then, he never recovered fully but managed to work intermittently and suffered from recurrence of ME/CFS symptoms (see Definition) plus insomnia. Some doctors thought he was suffering from post -viral fatigue.


At Breakspear Medical, a variety of tests were conducted on Mr TH. The significant test results were from:

  • The Fatigue Panel, which includes DNA adducts tests

    (looking for foreign particles adhering to DNA), showing

    that there were plastic particles present in his DNA

  • A Comprehensive Viral Panel showing active rubella,

    measles and Epstein-Barr Virus (EBV) infections

    Treatment & recovery

    The patient had treatment with antiviral drugs, including Aciclovir and natural antivirals, together with mitochondrial support and detox supplements. It was recommended that he stop using plastic water bottles (commonly used by cyclists) and not use any plastic involved in food storage, preparation or cooking. Six months later, his Fatigue Panel showed no plastic particles in his DNA, his Comprehensive Viral Panel results for rubella and measles antibodies were negative, although his EBV remained positive, and he had slightly improved energy.

    Nine months after starting treatment, the patient felt he


In order to be considered to have ME/CFS, a patient needs to have symptoms for at least six months and the symptoms must have begun or altered significantly since the onset. The patient, Mr TH, met these criteria.

The criteria considered for a diagnosis of ME/CFS are:*

  1. Fatigue

  2. Post-exertional malaise and/

    or fatigue

  3. Sleep dysfunction

  4. Pain

  5. Neurological/cognitive manifestations

  6. Autonomic manifestations (orthostatic intolerance, NMH, POTS etc.)

  7. Neuroendocrine manifestations (temperature regulation etc.)

  8. Immune manifestations
*Carruthers BM, Jain AK, De Meirleir KL, Peterson DL, Klimas NG, Lerner AM, et
al. Myalgic encephalomyelitis/chronic fatigue syndrome: clinical working case definition, diagnostic and treatment protocols. Journal of Chronic Fatigue Syndrome. 2003;11:7-115.

was starting to function well. His Comprehensive Viral Panel came back all clear and the patient became asymptomatic. He started to exercise again and

recommenced his hobby of cycling. His ATP (adenosine triphosphate, which is the main energy source for muscles and other tissues) levels had returned to a normal level.
At his recent review consultation, he reported feeling well and he is carrying on with our recommended maintenance supplement programme.


Taking an environmental history is a simple and effective way to evaluate where pollutant exposure may occur. As well, it is beneficial to take a holistic approach to health, including diet and supplementation, to complement the increasing specialisation in environmental healthcare.



Rebel without a biscuit
OK, disclaimer that I'm not science literate but I would think that plastics could be detected in human cells and tissues but DNA? How does that work.

And forgive me but I don't see how an antiviral flushes out plastic. According to research by scientists monitoring plastic (mostly in the oceans) everyone of us has plastic particles in our tissues as do all of the animals up and down the food chain that we eat.

The solution came off as quite simple yet I suspect some of the truly bad chemicals from microplastics might hide in fat tissue and be very hard to eliminate.

Maybe someone else knows more.


Senior Member
OK, disclaimer that I'm not science literate but I would think that plastics could be detected in human cells and tissues but DNA? How does that work.

And forgive me but I don't see how an antiviral flushes out plastic. According to research by scientists monitoring plastic (mostly in the oceans) everyone of us has plastic particles in our tissues as do all of the animals up and down the food chain that we eat.

Maybe someone else knows more.
Shhh, you're harshing their buzz ;-)


Senior Member
Some plastic compounds are aryl receptor inhibitors, which mean they may inhibit IDO1/IDO2 by this way.

(bisphenol, phtalate)

(They are also androgen receptor inhibitors, and testosterone was found to be efficient against fibromyalgia)

A subset of CFS/ME may be plastic induced.

I am myself a lady and feel much better since starting Testosterone + ambroxol+ Inosine, and I am thinking about avoiding plastic in my food, even if it seems quite a difficult task!!!!




Senior Member
Urinary phthalate metabolites are associated with decreased serum testosterone in men, women, and children from NHANES 2011-2012.

There is evidence of declining trends in T levels among men in recent decades, as well as trends in related conditions at multiple life stages and in both sexes. There is also animal and limited human evidence that exposure to phthalates, chemicals found in plastics and personal care products, is associated with reduced androgen levels and associated disorders.
To explore relationships between urinary concentrations of 13 phthalate metabolites and serum total T levels among men, women, and children when adjusting for important confounders and stratifying by sex and age (6-12, 12-20, 20-40, 40-60, and 60-80 y).
A cross-sectional study.
US National Health and Nutrition Examination Survey, 2011-2012.
US general population.
Serum total T measured by isotope dilution-liquid chromatography-tandem mass spectrometry.
Multiple phthalates were associated with significantly reduced T in both sexes and in differing age groups. In females, the strongest and most consistent inverse relationships were found among women ages 40-60 years. In boys 6-12 years old, an interquartile range increase in metabolites of di-2-ethylhexyl phthalate was associated with a 29% (95% confidence interval, 6, 47) reduction in T. In adult men, the only significant or suggestive inverse associations between phthalates (metabolites of di-2-ethylhexyl phthalate and dibutyl phthalate) and T were observed among men ages 40-60 years.
Because T plays an important role in all life stages for both sexes, future efforts should focus on better defining these relationships and their broader impacts.


Senior Member
Plastic exposure is sadly impossible to avoid completely these days, as it is used on almost all packaging products. It is found in tap and plastic bottled water, and even in fish. BPA free is often marketed as 'good' plastic. What is often not mentioned is that you ingest plastic particles and other leached chemicals like phthalates, BPF, BPS, PFC, or PVC. Even "healthy" producers and grocery stores that you trust surprisingly use a lot of toxic packaging. These are more toxic and oxidative stress hits to the body we do not need.

Another surprising one is US tap water, which is one of the most plastic polluted in world. Use your own cotton bags for bagging vegetables and groceries, avoid to-go packaging and cups, plastic water bottles, etc.. Buy glass bottled products as much as you can. Ask for ceramic or glass for your coffee shop trip, or bring your own. Get rid of plastic storage containers or cooking devices in the home. Do not use a plastic water boiler/cooker. Etc. Do what you can to lower the stress on the body.

We ME/CFS sufferers already are struggling with energy, so just imagine the amount of energy and nutrients needed in our bodies to process all these toxins every single day.
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