The link was wrong, he updated it in a response
https://www.sciencedirect.com/science/article/pii/S0306987722000822
https://www.sciencedirect.com/science/article/pii/S0306987722000822
Because this restoration of homeostasis is essentially a widespread recalibration of a complex system rather than the focused repair of a single point in the system, therapeutic reliance on one medication or supplement is liable to be less effective than the balanced therapeutic provision of a range of essential endogenous or exogenous elements that are used by the system to self-regulate.