Tom Kindlon to CO-CURE Apr 26
[sb: I hadn't seen this before and found nothing in advanced search. Is this related to the spinal tap study Cort participated in and wrote about? I don't see XMRV or retrovirus in the project terms, but the funding started this March.
Does anyone know anything more?]
http://tinyurl.com/32accoy i.e.
http://projectreporter.nih.gov/project_info_description.cfm?aid=7884022&icde
=3327409
Project Number: 1R21AI088765-01
Contact Principal Investigator: SCHUTZER, STEVEN E
Title: INFECTIOUS TRIGGERS IN CHRONIC FATIGUE SYNDROME
Awardee Organization: UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL
Abstract Text:
DESCRIPTION (provided by applicant): chronic fatigue syndrome (CFS) is a
major disabling illness of unknown etiology. It directly impacts more than
four million Americans. Infectious agents have been highly suspected but
none have ever been validated. Obstacles to their discovery have been lack
of a broad approach that can both detect the presence of multiple microbes
in a single sample and detect novel or variants of microbes. This has been
further hampered because more than 99% of all microbes cannot be cultured
and may go undetected.
In contrast to past limitations, we will use a new
approach that can surmount these obstacles. The discovery of potential
pathogens in cerebrospinal fluid of CFS would be field-altering in terms of
approach to the study of the disease and possible early detection,
prevention and treatment. This could be the gateway step to generate new
hypotheses and begin investigation into a microbe's causal association and
ways to prevent (egg vaccine) or counteract the effects of a microbial
pathogen.
PUBLIC HEALTH RELEVANCE: chronic fatigue syndrome is the major acquired
disease of productive adults. The cause remains unknown. If we can uncover
an infectious cause, which is suspected, diagnostics and therapies may be
developed to decrease costs and suffering to the individual and the burden
on our health care system and economy.
Public Health Relevance Statement:
Project Narrative chronic fatigue syndrome is the major acquired disease of
productive adults. The cause remains unknown. If we can uncover an
infectious cause, which is suspected, diagnostics and therapies may be
developed to decrease costs and suffering to the individual and the burden
on our health care system and economy.
Project Terms:
21+ years old; Adult; Agreement; American; Antiviral Therapy; Arthralgia;
Bacteria; Blood; Brain; CF patients; Causality; Cell Communication and
Signaling; Cell Signaling; Central Nervous System; Cerebrospinal Fluid;
Cerebrum; chronic fatigue Disorder; chronic fatigue syndrome; chronic
fatigue and Immune Dysfunction syndrome; chronic fatigue-Fibromyalgia
syndrome; Cognitive Disturbance; Cognitive Impairment; Cognitive decline;
Cognitive function abnormal; Data; Detection; Diagnosis; Diagnostic;
Disease; Disorder; Disturbance in cognition; Dysfunction; Early Diagnosis;
Encephalomyelitis, Myalgic; Encephalon; Encephalons; Etiology; Exclusion;
Exertion; fatigue; Freezing; Functional disorder; Genetic; Grippe;
Healthcare Systems; Human, Adult; Impaired cognition; Individual; Infectious
Agent; Infectious Mononucleosis-Like syndrome, chronic; Influenza;
Intracellular Communication and Signaling; Investigation; Investigators;
Joint Pain; Knee; Knowledge; Lack of Energy; Liquid substance; Lumbar
Puncture; MR Imaging; MR Tomography; MRI; Magnetic Resonance Imaging;
Magnetic Resonance Imaging Scan; Medical; Medical Imaging, Magnetic
Resonance / Nuclear Magnetic Resonance; Method LOINC Axis 6; Methodology;
Methods; Microbe; Muscle; Muscle Tissue; NMR Imaging; NMR Tomography;
Nervous System, Brain; Nervous System, CNS; Neuraxis; Neurologic;
Neurological; Nuclear Magnetic Resonance Imaging; Nucleic Acids; Onset of
illness; Operation; Operative Procedures; Operative Surgical Procedures;
Patient Self-Report; Patients; Physiopathology; Postviral fatigue syndrome;
Prevention; Protozoa; Protozoal; Publishing; Reporting; Research Personnel;
Researchers; Reticuloendothelial System, Blood; Royal Free Disease;
Sampling; Self-Report; Signal Transduction; Signal Transduction Systems;
Signaling; Sleep disturbances; Spinal Anesthesia; Spinal Puncture; Surgical;
Surgical Interventions; Surgical Procedure; Symptoms; syndrome; Systems,
Health Care; Testing; Vaccines; Variant; Variation; Virus; Viruses, General;
Zeugmatography; adult human (21+); base; biodefense; biological signal
transduction; cognitive dysfunction; cognitive loss; cognitively impaired;
cost; cystic fibrosis patients; design; designing; disease causation;
disease etiology; disease onset; disease/disorder; disease/disorder
etiology; disorder etiology; disorder onset; early detection; egg;
experience; flu infection; fluid; fungus; improved; infectious organism;
influenza infection; liquid; microbial; new approaches; novel; novel
approaches; novel strategies; novel strategy; pathogen; pathophysiology;
patients with CF; patients with cystic fibrosis; platform-independent;
prevent; preventing; public health relevance; spinal block; spinal fluid;
surgery; treatment of viral infectious disease
Other Information:
RFA/PA: PA-09-164
DUNS Number: 623946217
CFDA Code: 855
Study Section:
ZRG1 Project Start Date: 1-MAR-2010
Project End Date: 29-FEB-2012
Fiscal Year: 2010
Budget Start Date: 1-MAR-2010
Budget End Date: 28-FEB-2011
Administering Institutes or Centers: NATIONAL INSTITUTE OF ALLERGY AND
INFECTIOUS DISEASES
Project Funding Information for 2010: Total Funding: $273,000
Year Funding IC FY Total Cost by IC
2010 NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES $273,000
[sb: I hadn't seen this before and found nothing in advanced search. Is this related to the spinal tap study Cort participated in and wrote about? I don't see XMRV or retrovirus in the project terms, but the funding started this March.
Does anyone know anything more?]
http://tinyurl.com/32accoy i.e.
http://projectreporter.nih.gov/project_info_description.cfm?aid=7884022&icde
=3327409
Project Number: 1R21AI088765-01
Contact Principal Investigator: SCHUTZER, STEVEN E
Title: INFECTIOUS TRIGGERS IN CHRONIC FATIGUE SYNDROME
Awardee Organization: UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL
Abstract Text:
DESCRIPTION (provided by applicant): chronic fatigue syndrome (CFS) is a
major disabling illness of unknown etiology. It directly impacts more than
four million Americans. Infectious agents have been highly suspected but
none have ever been validated. Obstacles to their discovery have been lack
of a broad approach that can both detect the presence of multiple microbes
in a single sample and detect novel or variants of microbes. This has been
further hampered because more than 99% of all microbes cannot be cultured
and may go undetected.
In contrast to past limitations, we will use a new
approach that can surmount these obstacles. The discovery of potential
pathogens in cerebrospinal fluid of CFS would be field-altering in terms of
approach to the study of the disease and possible early detection,
prevention and treatment. This could be the gateway step to generate new
hypotheses and begin investigation into a microbe's causal association and
ways to prevent (egg vaccine) or counteract the effects of a microbial
pathogen.
PUBLIC HEALTH RELEVANCE: chronic fatigue syndrome is the major acquired
disease of productive adults. The cause remains unknown. If we can uncover
an infectious cause, which is suspected, diagnostics and therapies may be
developed to decrease costs and suffering to the individual and the burden
on our health care system and economy.
Public Health Relevance Statement:
Project Narrative chronic fatigue syndrome is the major acquired disease of
productive adults. The cause remains unknown. If we can uncover an
infectious cause, which is suspected, diagnostics and therapies may be
developed to decrease costs and suffering to the individual and the burden
on our health care system and economy.
Project Terms:
21+ years old; Adult; Agreement; American; Antiviral Therapy; Arthralgia;
Bacteria; Blood; Brain; CF patients; Causality; Cell Communication and
Signaling; Cell Signaling; Central Nervous System; Cerebrospinal Fluid;
Cerebrum; chronic fatigue Disorder; chronic fatigue syndrome; chronic
fatigue and Immune Dysfunction syndrome; chronic fatigue-Fibromyalgia
syndrome; Cognitive Disturbance; Cognitive Impairment; Cognitive decline;
Cognitive function abnormal; Data; Detection; Diagnosis; Diagnostic;
Disease; Disorder; Disturbance in cognition; Dysfunction; Early Diagnosis;
Encephalomyelitis, Myalgic; Encephalon; Encephalons; Etiology; Exclusion;
Exertion; fatigue; Freezing; Functional disorder; Genetic; Grippe;
Healthcare Systems; Human, Adult; Impaired cognition; Individual; Infectious
Agent; Infectious Mononucleosis-Like syndrome, chronic; Influenza;
Intracellular Communication and Signaling; Investigation; Investigators;
Joint Pain; Knee; Knowledge; Lack of Energy; Liquid substance; Lumbar
Puncture; MR Imaging; MR Tomography; MRI; Magnetic Resonance Imaging;
Magnetic Resonance Imaging Scan; Medical; Medical Imaging, Magnetic
Resonance / Nuclear Magnetic Resonance; Method LOINC Axis 6; Methodology;
Methods; Microbe; Muscle; Muscle Tissue; NMR Imaging; NMR Tomography;
Nervous System, Brain; Nervous System, CNS; Neuraxis; Neurologic;
Neurological; Nuclear Magnetic Resonance Imaging; Nucleic Acids; Onset of
illness; Operation; Operative Procedures; Operative Surgical Procedures;
Patient Self-Report; Patients; Physiopathology; Postviral fatigue syndrome;
Prevention; Protozoa; Protozoal; Publishing; Reporting; Research Personnel;
Researchers; Reticuloendothelial System, Blood; Royal Free Disease;
Sampling; Self-Report; Signal Transduction; Signal Transduction Systems;
Signaling; Sleep disturbances; Spinal Anesthesia; Spinal Puncture; Surgical;
Surgical Interventions; Surgical Procedure; Symptoms; syndrome; Systems,
Health Care; Testing; Vaccines; Variant; Variation; Virus; Viruses, General;
Zeugmatography; adult human (21+); base; biodefense; biological signal
transduction; cognitive dysfunction; cognitive loss; cognitively impaired;
cost; cystic fibrosis patients; design; designing; disease causation;
disease etiology; disease onset; disease/disorder; disease/disorder
etiology; disorder etiology; disorder onset; early detection; egg;
experience; flu infection; fluid; fungus; improved; infectious organism;
influenza infection; liquid; microbial; new approaches; novel; novel
approaches; novel strategies; novel strategy; pathogen; pathophysiology;
patients with CF; patients with cystic fibrosis; platform-independent;
prevent; preventing; public health relevance; spinal block; spinal fluid;
surgery; treatment of viral infectious disease
Other Information:
RFA/PA: PA-09-164
DUNS Number: 623946217
CFDA Code: 855
Study Section:
ZRG1 Project Start Date: 1-MAR-2010
Project End Date: 29-FEB-2012
Fiscal Year: 2010
Budget Start Date: 1-MAR-2010
Budget End Date: 28-FEB-2011
Administering Institutes or Centers: NATIONAL INSTITUTE OF ALLERGY AND
INFECTIOUS DISEASES
Project Funding Information for 2010: Total Funding: $273,000
Year Funding IC FY Total Cost by IC
2010 NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES $273,000
