Sushi
Moderation Resource Albuquerque
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Because grapefruit is a cytochrome P450 inhibitor? If that's the case then some medications can take a day or longer to clear the system. Your medication might be short acting, but if anyone's taking Prozac it's half life is at least 2-3 days and can take over a week to clear the system. Of course on the plus side, P450 inhibitors also increase the potency of your supplements. Bioperene is added to many supplements to "enhance absorption", but this is partially because it's a P450 inhibitor. I've been taking coenzyme q10 that has bioperene added to it, but I'm not sure if it's a good idea to take it or not. This is something I've been struggling with ever since learning about CYP450. Even if a person isn't taking any prescription drugs, taking P450 inhibitors can reduce your body's ability to detoxify. We are all exposed to hazardous chemicals such as xenoestrogens (also natural estrogens) and our bodies are constantly trying to eliminate them partially with the P450 enzymes. BTW, males also have plenty of naturally produced estrogen that can be toxic if not metabolized properly. This from Rich
Yes, because grapefruit is a P450 inhibitor. The jury is out about grapefruit seed extract--I have read conflicting opinions, but in my experience is does seem to be, so yes, it is important to consider the half lives of the drugs you are taking.
Sushi