Nutritional deficiencies and predictors of mortality in diabetic and nondiabetic gastroparesis, 2021

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Nutritional deficiencies and predictors of mortality in diabetic and nondiabetic gastroparesis - PMC (nih.gov)


Background
Gastroparesis is a debilitating condition that may impact morbidity and mortality, but there is a lack of long-term studies examining this relation.
The aim of this study was to determine the predictors of mortality in gastroparesis and to determine the nutritional deficiencies.


Results

Of the 320 patients, 46 (14.4%) died during the study period.

Among diabetics,
advanced age (hazard ratio [HR] 1.06, 95% confidence interval [CI] 1.03-1.10; P<0.001),
chronic kidney disease (CKD) (HR 4.69, 95%CI 1.62-13.59; P=0.004), and
malnutrition (HR 10.95, 95%CI 3.23-37.17; P<0.001) were associated with higher mortality,

whereas in nondiabetics
older age (HR 1.05, 95%CI 1.01-1.09; P=0.04),
CKD (HR 10.2, 95%CI 2.48-41.99; P=0.001),
chronic obstructive pulmonary disease (COPD) (HR 7.5, 95%CI 2.11-26.82; P=0.002),
coronary artery disease (CAD) (HR 9.7, 95%CI 1.8-52.21; P=0.008), and
malnutrition (HR 3.83, 95%CI 1.14-29.07; P=0.03) were associated with increased mortality.

Overall,
48.8% had vitamin D,
18.2% had vitamin B12, and
50.8% had iron deficiencies.

Only 19.4% of the whole cohort was evaluated by a nutritionist.