It looks like the nucleotides I posted about earlier could cause problems. Especially since I have Lyme. Stimulating a Th1 immune response will likely increase inflammation. I've been experiencing depression for the past 4 months and it seems to be due in part to inflammatory cytokines. Anything that causes a herx (such as probiotics or antifungal/antibacterial/antimicrobial supplements) seems to trigger a response. It's likely that the immune system supplements I'm taking are also contributing to the problem.