John Mac
Senior Member
- Messages
- 321
- Location
- Liverpool UK
https://upload.umin.ac.jp/cgi-open-bin/ctr_e/index.cgi
UMIN000029076
2017/09/12
Development of surrogate biomarkers for ME/CFS Myalgic encephalomyelitis/chronic fatigue sydnrome (ME/CFS) and healthy control
Primary outcomes:
The level of brain positive inflammation dected by positron emission tomography (PET), [F18]DPA-714
Key secondary outcomes:
Oxidative stress level, Anti-oxidant activity, Metabolome, Proteome, Cytokines, Extracellular vesicles, Clinical test (CRP, cholesterol, etc.), CD antibody, Autonomic nervous system, Questionnaires for fatigue, depression and various symptoms, Arithmetic task, Sleep-wake cycle, Performance status for fatigue
Target sample size:
120
Name of lead principal investigator Yasuyoshi Watanabe
Organization Osaka City University
Division name Graduate School of Medicine