My gut issues started when I developed CFS. They are pretty much constant and debilitating with alternating diahorrea and constipation, pain, bloating, nausea, gastric reflux etc. I have had some improvement with diahorrea after starting probiotics and I'm now on an elimination diet for grains, fructose, numerous identified food allergies and natural and artificial food chemicals. When my gut is bad my CFS symptoms are worse.