MTHFR anxiety treatment news article

[Adster]

Good to see this in the mainstream news:

http://www.news.com.au/national/sou...e-for-the-future/story-fnii5yv4-1227251037624

 

[ahmo]

@Adster this is really excellent!

 

[PennyIA]

I really like that they took the time to spell out that folinic acid is NOT the same as folic acid... it's nice to see it get a nice, long article like this spelling out that it's more common than realized and how it does help many people.

 

[Bob]

The article mentions fibromyalgia once, and also depression, autism, ADHD, miscarriage, stroke, migraine, hypertension, and other issues. Overall, it's an article about a specific genetic mutation in relation to methylation.

Six months ago I discovered my methylenetetrahydrofolate reductase gene, known broadly (and aptly) as MTHFR, is a bit wonky. Specifically, I inherited variations in the MTHFR gene, at the particular locations of C677T and A1298C, predisposing me to high levels of homocysteine.

This is a chemical found in a metabolic cycle called methylation that relies heavily on B-vitamins and plays an important role in, among many other things, mood regulation. MTHFR, when working properly, synthesises folate into a specific form needed to turn toxic metabolite homocysteine into methione, which is essential for cell growth and DNA metabolism.

 

[Bob]

The treatment it recommends is folinic acid (the bioavailable form of folic acid) and
methylcobalamin B12. And a difference should be seen after 4 weeks. I didn't see anything about dose size.