Hi Dreambirdie,
Yes, color makes forums and life fun!
I think the easiest way to answer some of these questions is to quote from previous posts Rich has done on other forums. He has always OK'ed us sharing information this way in the past.
And yes, Rich's Simplified Protocol has helped me a lot. I know it has corrected some basic things--like my diurnal cortisol curve was normal for the first time after being on the protocol for about 9 months. Generally I don't crash much now--the main problem is getting into heavy-duty detox reactions as I have been sick for decades and have accumulated a big mess of toxins. I am now sweating though
(what a weird and wonderful thing to rejoice at being able to sweat!
) and use FIR saunas and epsom salts baths to help move on out all the
gems that my newly active detox system has started to deal with.
OK, actifolate: Rich used to recommend something by metagenics called Intrinsi/B12/folate because he feels that it is important to get the right amount of folinic acid. Metagenics changed this product, so now he recommends actifolate for the same reason. To quote Rich:
"I've learned that Metagenics has recently changed the formulation of its product Intrinsi/B12/folate without changing the name of the product. It no longer contains folinic acid (5-formyl tetrahydrofolate). Metagenics also supplies Actifolate, which does continue to contain folinic acid, as well as folic and 5-methyl tetrahydrofolate. So I'm suggesting that in the future, people doing the simplified treatment approach should substitute Actifolate for Intrinsi/B12/folate, using the same dosage, i.e. one-quarter of a tablet. FolaPro should continue to be used also, as in the past."
Both these forms of folate are necessary to restore methylation.
And the order to start taking the supplements--Rich wrote this in June 09, so it should still be current:
"I generally suggest starting with the multi and the phos. serine complex, because they support the basic metabolism and help to correct any deficiencies that might be present in the essential nutrients.
"Then I generally suggest that people start a few days later with the folate-containing supplements, at the suggested dosages, and then add the hydroxocobalamin a few days later. If the detox symptoms become intolerable, it's O.K. to stop all the supplements to calm them down, and then proceed. People seem to need different dosages, and have to experiment a little to see what works for them. I do not recommend going higher than the recommended dosages for the folate-containing supplements, at least until a person has been on the treatment for a while, because some people have experienced detox symptoms that have momentum, and do not stop right away when they stop the supplements, if the dosage has been high.
"As always, I want to state my position that it's necessary for a person to be monitored by a physician while on this treatment, even though it consists only of food supplements, because it can have profound effects, especially in people who have some other conditions along with CFS, and a few people have had some serious adverse effects, as I have written."
Most people find it is best to start with a
tiny, tiny doses (a sprinkle or a crumb) of the folates, the B12, and the multi. I think it is best to start the supplements in the order he suggests and take each one for a few days to make sure you are not reacting to it--sometimes the reactions appear only after a few days. When you feel stable with all the supps, you can start raising the doses, one by one and monitoring your response. I think it took me about 3 months to get up to the recommended doses.
As far as costs and the multi, Rich recommends this multi because it has several key ingredients that support methylation that will not be found in other multis. Also, you do not want to take a multi that has any folic acid or B12 as it is likely to be a different form and can "grab" the receptors for that nutrient and prevent the bioactive ones in the protocol from getting a chance at the receptors.
The costs are really minimal as you cut up the pills and take tiny doses. I think the first 3 months of supplements cost me about $100. And the only one that you need to get from Holistic Heal is the multi--there are less expensive sources on the internet for the others.
After being on these supps for nearly 2 years, I have found that I need to reduce the doses from the recommended ones--presumably because methylation is working better now and I don't need as much. (Rich confirmed this as likely--at least in my case) So I spend very little still on these supplements.
Because you don't get enough of the basic nutrients from the multi,
most of us supplement other vitamins separately--like some of the B's, D3, etc.
Hope this helps! Everyone responds differently to these supps, so if you try it, just go very slowly and watch your body.
Best wishes,
Sushi