I really think you are onto something with me. So, for that, I thank you. Question about B2...after taking approximately 100mg of FMN/R5P spaced throughout the day (25mg each), I have been feeling so much better with regards to anxiety, energy, brain fog, depression, etc. I didn't reread this thread update and have still been taking b12 and folinic acid, and did have some fog/nervousness in the afternoon. I am going to back off the b12 for a while.