Methyl Trap, Paradoxical Folate Deficiency or...

[GreenMachineX]

Update: so the extra doses of methylfolate have produced extreme relaxation, to the point of needing some caffeine to counter it. But, it only lasts 3-4 hours. Yesterday I totaled 800mcg methylfolate and 250mcg methylcobalamin and 250mcg adenosylcobalamin. I’m going to see what splitting that between 12 hours does, as I took the second half of that around lunch so I had tightened back muscles and palpitations and worsening angular cheilitis by bed time. It also seems that vegetable folates, folinic/folic acid all give me shortness of breath.

@Freddd do you have any thoughts on this? Does it sound like I just need more methylfolate over all?

 

[alicec]

@dannybex @alicec
How do you guys break up your doses of b12/folate? All at once, just morning, before bed, etc?

I apply the whole B12 dose when I first get up. Note this is topical which has different uptake characteristics. If you are using sublingual you'd probably be better off spreading out smallish doses over the day.

I divide the methylfolate into 3 doses spread over the day, taking the first at the same time as B12.

 

[dannybex]

@dannybex @alicec
How do you guys break up your doses of b12/folate? All at once, just morning, before bed, etc?

I also take my dose of B12 in the morning, then a little folinic after breakfast, but save most of it for after dinner as it helps me sleep. But I think I need to spread it out more evenly so that it will (hopefully) help me relax as well during the day.

Seriously, it helps me get into that deeper dream-like sleep*, but if I take more than 400-600mcgs after breakfast, I'll sleep so deeply that I can't hear my alarm. A couple days ago I overslept by more than an hour. Not good.

*I seem to be the only one on this forum where this happens, so take it with a grain of salt.

 

[GreenMachineX]

Not sure if anyone from this group is still around...but when making changes to b12, folate, etc, how long should the dose be held before making another change?

 

[TinaT]

[QUOTE="alicec, post: 990633, member: 16804".

There is no ideal dose - you need to work it out empirically. You may find that with time the increased need will moderate.[/QUOTE]
Do you know how much time? I mean on average?