THERAPEUTIC PLAN FOR CHRONIC FATIGUE SYNDROME/ MYALGIC ENCEPHALOMYELITIS, FIBROMYALGIA AND OTHER DISEASES WITH CHRONIC FATIGUE AND OTHER SYMPTOMS ASSOCIATED WITH HYPOPERFUSION.
As with Chronic COVID or Long COVID, treatments against Microbial Load and against persistent Biofilms and BioClots are the main objectives of the Therapeutic Plan for CFS/ME and FM.
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Several scientific publications have shown the existence of Persistent Infections due to Herpesvirus, other viruses or other intracellular microorganisms in patients with CFS/ME, Fibromyalgia (FM) and other diseases that present with Chronic Fatigue and other symptoms associated with Hypoperfusion.
It must be taken into account that in very persistent chronic infections there is usually the presence of Biofilms, which constitute a protective barrier and significantly reduce the entry and effect of drugs against the Microbial Load and thus facilitate the microorganisms to generate endurance.
In 80% of CFS/ME patients, the presence of clots with a high fibrinamyloid content has been evidenced, which, because they fulfill similar functions to Biofilms, we have proposed to call them BioClots.
We consider CFS/ME, Fibromyalgia (FM) and Chronic COVID or Long COVID to be Biofilm-based diseases.
Having as reference and based on extensive successful experience of our Treatment Schemes and Protocols for patients with Chronic COVID or Long COVID, this document presents a proposal for a Therapeutic Plan for patients with CFS/ME, FM and other diseases with Chronic Fatigue and other symptoms associated with hypoperfusion.
This Plan consists of 3 Objectives or Lines of Action:
1) Reduce the Microbial Load.
2) Break Down Biofilms and Persistent BioClots and Reduce Platelet Hyperactivity.
3) Treat Depletion of Nutrients, Hormones and other substances, the Oxidative Stress and Immune Dysfunctions.
The First Line of Action is the main one, since it is aimed at reducing the Microbial Load, which is the cause that triggers the problems covered by the other 2 Lines of Action. If an effective treatment is given against the Microbial Load, most of the negative effects that this has caused in the organism will be reversed, but in general, some degree of sequelae will remain, which is usually minor, which can be minor if they take action in time.
Next in importance is the goal of Break down Biofilms and Persistent BioClots.
Considering these 3 Objectives or Lines of Action, it will be necessary to choose which medications, supplements or procedures to include for each one of them. To make this decision, it is necessary to investigate which are the causative organisms, for this the history of infections should be asked and the analyzes and other tests carried out on the patient should be reviewed. It is also important to see the frequency of certain infections in the place where the patient lives.
Given the high percentage of resistance to antimicrobial drugs present in persistent infections, it is recommended to include in the Treatment Plan Procedures that have a significant effect in reducing the microbial load. Of these, therapies with Ozone gas (O3) have been shown to be effective in reducing the load of viruses, bacteria and other microorganisms.
Other Procedures to consider are HELP Apheresis, HOCTT, Ozone Sauna packages and Hyperthermia Therapies, among others.
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