I think this explains a bit how it might help people with ME/CFS:I try to keep an open mind but I fail to see how this trial will lead to effective treatment, or any better understanding of this disease.
I think it does sound too good to be true, but maybe they'll learn something that can be helpful. We won't know if this is never tried.TMS can also be used to study the brain, and that’s how it’s mostly been used in ME/CFS. Several ME/CFS studies in the early to mid 2000s found reduced motor cortex excitability. That suggested that at least part of the fatigue in ME/CFS was “central”; i.e. it emanated from the brain, and that ME/CFS brains may be having difficulty activating the muscles during exercise.
Except for a small Japanese case series, and a small open label trial, rTMS has been little studied as a treatment option in ME/CFS. The case series, though, concluded that, “In most of the patients, treatment resulted in an improvement of fatigue symptoms”, and the open label trial found that both people with mild/moderate or severe cases of ME/CFS significantly benefitted. It called rTMS “a novel therapeutic intervention for ME patients” and concluded that:
“rTMS can improve fatigue symptom in ME patients regardless of (the )baseline severity of (the) fatigue symptoms”.
I hope it goes much better for those in this study.
but I don't think I will be able to take part, as no anti-depressants are allowed, even in the tiny doses I take
I may try instead to have the treatment itself, provided insurance is willing.
I could only imagine that it’s the same like in Germany where you can obtain this treatment when antidepressants fail to work. Otherwise insurance won’t cover it here.thats too bad, how frustrating.....
Is there anywhere to obtain the treatment? it sure sounds tempting....
thats too bad, how frustrating.....
Semel Institute for Neuroscience and Human Behavior
University of California Los Angeles
The Suthana Lab in the Semel Institute is running the clinical trial. You get assigned randomly to the control group or the treatment group, but anyone who lands in the control group is offered the real deal at the end of the trial. The trial itself is quite intensive: basic medical assessment with info on medications and diagnoses; a three hour psychological assessment focussing on memory; then 15 sessions over three weeks, each taking about an hour to an hour and a half; a final psych assessment. There's a small honorarium and they give valet parking, which is cool, given the price of parking in Westwood. Normally husband and I travel in by bus, but that's out for the duration! If you are interested in the trial, contact Sonja Hiller (SHiller@mednet.ucla.edu).
I will find out whether I can get the treatment anyway, as it looks like I can't manage without my teensy-weensy dosy of Doxepin, and I will post any updates.