The problem is most of the research has been done on cfs not ME, fuduka criteria etc are what have been used. This criteria was used in the bond uni nk function study. SO alot of the information about low nk function and viral titres is more related to cfs and not ME. so if cfs and ME are very different, then alot of these experimental treatments etc if a cfs criteria was used to select patients then it may not be applicable to ME. Personally i think we will find it is mostly the same thing, the difference will be severity, types of infections and how deep these infections have gone and what damage is done. When people say ME is more neurological then cfs, i think ME people just have different parts of their nervous system damaged and maybe more severly.