seems the benefit might be more about cleaning the bowels and may help with inflammation from that pathway to the brain, I have chronic sinusitis and rhinosinusitis and anaphylaxis and anaphylatoid reactions to mold extracts amoung other things , chemicals,voc's, basicly brain allergy immediate severe reactions in the brain that quickly send you to lala land and causes mood changes with re-exposure to my triggers, washing my sinuses helps stop the continuation of immediate effects from re-exposure, the last few years the intencity of the reactions over all has mellowed out a little where I can get out a little more but depending on dose still and to what I can still go to lala land, kindling effects are likely involved and I think that's mast cells in the brain, I think as far as water damaged building exposures go it's likely the overall changes in biome and molecular mimicry that leads to autoimmunity and because the innate and acquired immune systems are involved and mast cells and IL-33 are the bridge between innate and acquired that it's very possible that MCAD may happen along with infection going systemic, BBB breakdown, and other airway involvement to the brain (specifically sinus /brain for me is very involved in my severe fibromyalgia and what brings own my severe fibromyalgia is a re-exposure to a trigger, my triggers are what I was exposed to in the WDB that tried to kill me. and with secondary responces basicly the whole airway is involved, avoidance is number one on the list of things to do , not just in the air but food, skin. ).