Well for example, last night, I took more potassium than I think I ever had. Several times before bed. And then woke up this morning with the worst muscle twitching in months and months, if not longer.
I use potassium bicarbonate as it's the cheapest by weight and helps counter metabolic acidosis. A quarter teaspoon is approximately 400 milligrams of potassium. I probably had 1,200 mgs potassium -- at least -- in the 4-5 hours before bedtime.
Unfortunately I can't tolerate tomatoes due to histamine intolerance, so no V-8 for me. I tend to do better with sodium as well, although I used lite-salt due to increase blood pressure over the last six years.
I can't find the posts right now, but there are many that involve both b12 and folate and either one -- or both -- affecting potassium needs. The irony in all of this for me, is back in 2003 I was prescribed methyl-b12 shots along with nebulized glutathione. Within 2 days a year of twitching, irritability and most of my anxiety calmed way down and started about a year or more of an 80% remission. And never once was the need for potassium even mentioned.
Perhaps I need to try sourcing glutathione again, or trying n-acetylcysteine. Rich Van Konynenburg repeatedly said that starting up methylation could temporarily deplete glutathione, especially with higher doses of B12s and folates. And I didn't have any issues with agitation, twitching, etc., cramping when I was prescribed it back in 2003. Unfortunately that doctor is halfway across the country now...