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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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how severe are you?
I vacillate between severe and the low end of moderate. All depends on my physical and mental exertion. If I do absolutely nothing for a week, I am low end of moderate. Unfortunately, that's not living, but you all know that already .....
I will post back if I learn any additional information on low CD8. All I know thus far is very vague. One doctor suggested it is a common finding in autoimmune diseases. Another individual suggested that it could be related to HHV-6 and it's ability to shift T-cell expression from CD8 to CD4. That activity is why HHV-6 is considered an HIV "helper" virus. I have not seen any documentation that suggests this CD8>CD4 shift would show up in standard lymphocyte blood work.