Link Between CCI and the Markov CBIS bacterial dysbiosis theory of ME/CFS?
Dr Igor Markov in the Ukraine say he has found the cause and the cure of ME/CFS: he believes ME/CFS is due to a chronic bacterial dysbiosis in the kidneys, and sometimes also in the nasopharynx (the nasopharynx is an area located just above the back of the throat).
He says these bacterial dysbioses release bacterial toxins into the bloodstream, and it is this constant intoxication with potent bacterial toxins which causes the symptoms of ME/CFS. By testing the blood of his ME/CFS patients, Dr Markov found most patients have severely high levels of bacteria toxins in their bloodstream.
Dr Markov treats these bacterial dysbioses with autovaccines (autogenous vaccines) which target and kill the bacteria, and says autovaccine therapy completely cures ME/CFS in 93% of cases.
A post summarizing the Markov theory of ME/CFS is HERE.
A Markov discussion thread is HERE.
Anyway, I was thinking that these same bacterial dysbioses that Dr Markov finds in ME/CFS could also be the cause of craniocervical instability (CCI).
Bacteria not only release bacterial toxins, but can also secrete connective tissue-destroying matrix metalloproteinase (MMP) enzymes like elastase and collagenase. In addition, the immune system when it fights bacteria will also release MMPs, which unfortunately destroy connective tissues as collateral damage.
So given that the nasopharynx is right next to the area where the weakened connective tissue (ligaments) of craniocervical instability are found, could the constant release of bacterial toxins and MMP enzymes from this nasopharynx bacterial dysbiosis be the cause of CCI in ME/CFS patients?
The ligaments of the craniocervical junction are found weakened and lax in CCI patients, and this weakness is due to the connective tissue of the ligaments being damaged.
The Nasopharynx is Located Right Next to the Craniocervical Instability Area
When I tested my own urine for bacteria, and when I was tested by the Markov Clinic bacteriology department, it became apparent that I had three bacteria in my urine, including Klebsiella pneumoniae.
I then tested some nasal mucus that I obtained by blowing my nose, and this was also positive for Klebsiella pneumoniae.
So this indicates a the presence of bacteria in my nose or nasopharynx.
I use chromogenic agar to help identify bacterial pathogens. Agar is a nutrient medium on which bacteria can be grown, and chromogenic agar is a special type of agar which turns different colors depending on what species of bacteria is growing on it.
So when I placed some nasal mucus on my chromogenic agar, some bacterial colonies grew, and the color suggested Klebsiella pneumoniae.
If a local nasopharynx bacterial dysbiosis is causing the CCI, possibly even simple treatments like Dr Joseph Brewer's and Dr Ritchie Shoemaker's antimicrobial nasal sprays might be beneficial.
In both cases, these nasal sprays contain a biofilm buster (EDTA) which can break down the biofilms of any pathogen. It is the biofilms which allow a pathogen to create a chronic dysbiotic overpopulation. You can also make your own biofilm busting nasal spray just by using a 1% N-acetyl cysteine (NAC) solution.
However, it may be that the bacterial dysbiosis in the kidneys is also releasing MMP enzymes into the bloodstream, so in addition to a nasopharynx dysbiosis, this kidney dysbiosis could be a further contributory factor to CCI.
According to Dr Markov's published study on more than 4000 of his ME/CFS patients, the autovaccine approach to treating these bacterial dysbioses in the kidneys and nasopharynx is 93% successful in completely curing ME/CFS (curing meaning back to normal health with no further ME/CFS symptoms, and no further treatment required).
Dr Igor Markov in the Ukraine say he has found the cause and the cure of ME/CFS: he believes ME/CFS is due to a chronic bacterial dysbiosis in the kidneys, and sometimes also in the nasopharynx (the nasopharynx is an area located just above the back of the throat).
He says these bacterial dysbioses release bacterial toxins into the bloodstream, and it is this constant intoxication with potent bacterial toxins which causes the symptoms of ME/CFS. By testing the blood of his ME/CFS patients, Dr Markov found most patients have severely high levels of bacteria toxins in their bloodstream.
Dr Markov treats these bacterial dysbioses with autovaccines (autogenous vaccines) which target and kill the bacteria, and says autovaccine therapy completely cures ME/CFS in 93% of cases.
A post summarizing the Markov theory of ME/CFS is HERE.
A Markov discussion thread is HERE.
Anyway, I was thinking that these same bacterial dysbioses that Dr Markov finds in ME/CFS could also be the cause of craniocervical instability (CCI).
Bacteria not only release bacterial toxins, but can also secrete connective tissue-destroying matrix metalloproteinase (MMP) enzymes like elastase and collagenase. In addition, the immune system when it fights bacteria will also release MMPs, which unfortunately destroy connective tissues as collateral damage.
So given that the nasopharynx is right next to the area where the weakened connective tissue (ligaments) of craniocervical instability are found, could the constant release of bacterial toxins and MMP enzymes from this nasopharynx bacterial dysbiosis be the cause of CCI in ME/CFS patients?
The ligaments of the craniocervical junction are found weakened and lax in CCI patients, and this weakness is due to the connective tissue of the ligaments being damaged.
The Nasopharynx is Located Right Next to the Craniocervical Instability Area
When I tested my own urine for bacteria, and when I was tested by the Markov Clinic bacteriology department, it became apparent that I had three bacteria in my urine, including Klebsiella pneumoniae.
I then tested some nasal mucus that I obtained by blowing my nose, and this was also positive for Klebsiella pneumoniae.
So this indicates a the presence of bacteria in my nose or nasopharynx.
I use chromogenic agar to help identify bacterial pathogens. Agar is a nutrient medium on which bacteria can be grown, and chromogenic agar is a special type of agar which turns different colors depending on what species of bacteria is growing on it.
So when I placed some nasal mucus on my chromogenic agar, some bacterial colonies grew, and the color suggested Klebsiella pneumoniae.
If a local nasopharynx bacterial dysbiosis is causing the CCI, possibly even simple treatments like Dr Joseph Brewer's and Dr Ritchie Shoemaker's antimicrobial nasal sprays might be beneficial.
In both cases, these nasal sprays contain a biofilm buster (EDTA) which can break down the biofilms of any pathogen. It is the biofilms which allow a pathogen to create a chronic dysbiotic overpopulation. You can also make your own biofilm busting nasal spray just by using a 1% N-acetyl cysteine (NAC) solution.
However, it may be that the bacterial dysbiosis in the kidneys is also releasing MMP enzymes into the bloodstream, so in addition to a nasopharynx dysbiosis, this kidney dysbiosis could be a further contributory factor to CCI.
According to Dr Markov's published study on more than 4000 of his ME/CFS patients, the autovaccine approach to treating these bacterial dysbioses in the kidneys and nasopharynx is 93% successful in completely curing ME/CFS (curing meaning back to normal health with no further ME/CFS symptoms, and no further treatment required).
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