Dr. Friedman - The Future for CFS Research
Wednesday, 12 October 2011
Ken: Well the research definition that seems to be used is something called the Fukuda case definition, Fukuda et al, which dates back to 1994, and that definition has been used since that date forward. It is much more restrictive a case definition than one would like to see used on patients, but it helps to define a patient population that is relatively suffering from similar symptoms and so therefore for research purposes you are apt to get results that are clearly defined
Interviewer: So it's a conservative definition
Ken: A conservative definition that may exclude some patients and therefore is not workable in a clinical situation.
In the clinical situation, you want something that is more relaxed, or a more inclusive definition, and there are actually a couple of those. There's what's called the Canadian case definition, which was developed in 2003, 2004, and that seems to be very good at identifying patients and their key symptoms, and having them diagnosed as having Chronic Fatigue Syndrome and then there is a brand new one that has been developed in 2011 that is called the International case definition, and that one is essentially too new for anyone to have any sense of how it will fare, as either a patient case definition or as a research case definition.
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