frozenborderline
Senior Member
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So it seems like itraconazole has a serious interaction with benzodiazepines because of its effect on liver enzymes that metabolize benzodiazepines?
I have to take itraconazole for a fungal infection in my lungs and am dependent on benzodiazepines prescribed by a different doctor. Since I'm dependent I cant just stop but I also need to take the itraconazole.
How significant is the pharmacokinetics of the interaction? How much can I expect it to potentate benzos ? Does it matter how much time between the dosing there is?
The doctor didn't seem too concerned about the interaction but it came up as serious online.
Also wondering if the same liver enzymes affect metabolism of antihistamines like benadryl , which I also take daily.
I have to take itraconazole for a fungal infection in my lungs and am dependent on benzodiazepines prescribed by a different doctor. Since I'm dependent I cant just stop but I also need to take the itraconazole.
How significant is the pharmacokinetics of the interaction? How much can I expect it to potentate benzos ? Does it matter how much time between the dosing there is?
The doctor didn't seem too concerned about the interaction but it came up as serious online.
Also wondering if the same liver enzymes affect metabolism of antihistamines like benadryl , which I also take daily.