ChookityPop
Senior Member
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It is about* time to take chronic enterovirus seriously.
Just found this article from last year. I translated it from Norwegian in Google translate.
"Chronicle: Werner Frøynes, pharmacist, cand.pharm. and pharmacy entrepreneur in convalescence
PATIENTS SUFFERING from myalgic encephalopathy (ME), fibromyalgia, Lyme disease or other tick-borne infections, understand that the health care map does not match the terrain. When an examination in the Norwegian health service does not reveal illness, and even less the cause of this, many patients seek help abroad.
The less resourceful have to deal with their ailments, often with significant loss of quality of life - or at worst loss of life.
LONG TERM ANTIBIOTIC COURSE. I myself have been on a futile journey within the Norwegian health care system. I was, at three-month intervals, referred to constantly new wards at Haukeland University Hospital. I did not receive a significant answer, despite a disabling symptom picture.
The rescue was to leave Norway. At a clinic in Germany, samples were taken where the answers matched the terrain. The tests revealed several bacterial infections, as well as high antibodies to a specific enterovirus. Back in Norway, I experienced that the doctors were most concerned with talking down the German analysis methods.
A long-term course of antibiotics from the clinic in Germany slowly made me better, in line with regular test results from the same place. Eventually, the bacterial infections were defeated, but still the improvement slowed down. The antibodies against the enterovirus were still at a high level. In all probability, the viral infection was a more important part of the disease than we had assumed.
VIRUS UNDERSTANDING. The pandemic with covid-19 has illustrated that medical science has a way to go when it comes to understanding viral infections. Why do some people get sick and die from the coronavirus, while others barely notice that they are infected? Nor is the development of immunity to the coronavirus understood. Medical science seems to have the same challenges when it comes to understanding enterovirus.
Enterovirus is a viral family that causes serious illness. A book written by the English physician John Richardson describes 7,000 patients with chronic infections caused by enteroviruses. Many of these patients underwent a development in which the viral infection started in the gastrointestinal tract, passed into nearby muscles - and from there found its way into the thoracic spine. There, the virus damaged nerves and muscles, often with the result that patients had pronounced dizziness (labyrinthitis) and wing-leafing. It's like reading my story.
CAUSE OF SEVERAL CONDITIONS? The Enterovirus Foundation (EVF) is a foundation in the United States that works to increase knowledge about enterovirus. Their "Board of Directors" includes several professors and researchers in the field. The foundation points to enterovirus as the cause of a number of diseases and conditions.
Some of these associations are recognized in medical science, such as myocarditis, type 1 diabetes, hand-foot and mouth disease, meningitis and severe chest pain.
EVF also points to studies that suggest that enteroviruses may play a role in diseases that medical science does not understand the cause of, such as ME.
Coxsackievirus is a type of enterovirus with affinity for musculature. It is my claim, and experience, that infection of the muscles of the thoracic spine with this type of virus must be an important cause of somatic tinnitus (tinnitus). This is supported in the literature by case studies and other literature.
Tinnitus is a symptom that is not understood, so here there is an obvious need for more research!
DIAGNOSIS - FIRST CHALLENGE. In order to detect enterovirus, PCR technology is used in Norway - virus RNA is detected in blood and faeces, among other things - something EVF claims is only reliable in acute illness. The EVF claims that the use of PCR leads to false negative test results in more than 70 percent of cases where there is in fact a chronic enterovirus infection. EVF therefore recommends instead the use of immunohistochemistry or serology, which the laboratory in Germany has used for me a number of times. In all cases, the levels of my antibodies have been 6-60 times above what EVF claims are signs of chronic infection. This is met with a shrug by my current doctor, a professor at Rikshospitalet. "We believe in PCR," is the answer from there.
The guidelines for diagnostics in Norway are based on the recommendations of the European Non-polio Enterovirus Network (ENPEN). Der heter det: «Furthermore, there is a high prevalence of EV antibodies in the general population from previous exposure and, thus, serologic testing lacks clinical specificity».
Here, ENPEN chooses to ignore all levels of antibodies because antibodies to enterovirus are common in the population. This is contrary to what EVF writes: «The Micro-neutralization test is a very sensitive, specific test and only 11 enteroviruses, coxsackie B1-6 and echoviruses 6, 7, 9, 11, and 30 can be tested using this method. Titers of 1: 160-320 and higher are good indicators of current infection ».
Does chronic enterovirus infection go under the radar because the Norwegian healthcare system follows ENPEN's recommendations for diagnostics?
THINK OUTSIDE THE BOX! For school medicine, it is obviously very difficult to adjust the map. Any change in the paradigm is made on the basis of evidence, often on the basis of large international, randomized, double-blind clinical trials. This is understandable, but it should be remembered that several major advances in medical science have sprung from findings in individual patients.
In our system, it is clear that findings in individual patients do not lead doctors to take new paths and think new thoughts, even if a connection can be made probable. As in my case: both with literature and a lot of validated blood samples from accredited laboratory. Has the requirement for conformity and arrangement in the ranks become too great? I would argue that this lack of commitment and professional curiosity on the part of the doctors is a betrayal of the patients.
My message is that medical science must now take enterovirus seriously. It is likely that this viral family is a major cause of serious, chronic disease in the population. The message from the Enterovirus Foundation must be verified. If it can be established that PCR does not detect chronic enterovirus infection, other methods must replace PCR as a diagnostic tool. Then we can start discussing how to fight chronic disease caused by this destructive virus family."
Just found this article from last year. I translated it from Norwegian in Google translate.
"Chronicle: Werner Frøynes, pharmacist, cand.pharm. and pharmacy entrepreneur in convalescence
PATIENTS SUFFERING from myalgic encephalopathy (ME), fibromyalgia, Lyme disease or other tick-borne infections, understand that the health care map does not match the terrain. When an examination in the Norwegian health service does not reveal illness, and even less the cause of this, many patients seek help abroad.
The less resourceful have to deal with their ailments, often with significant loss of quality of life - or at worst loss of life.
LONG TERM ANTIBIOTIC COURSE. I myself have been on a futile journey within the Norwegian health care system. I was, at three-month intervals, referred to constantly new wards at Haukeland University Hospital. I did not receive a significant answer, despite a disabling symptom picture.
The rescue was to leave Norway. At a clinic in Germany, samples were taken where the answers matched the terrain. The tests revealed several bacterial infections, as well as high antibodies to a specific enterovirus. Back in Norway, I experienced that the doctors were most concerned with talking down the German analysis methods.
A long-term course of antibiotics from the clinic in Germany slowly made me better, in line with regular test results from the same place. Eventually, the bacterial infections were defeated, but still the improvement slowed down. The antibodies against the enterovirus were still at a high level. In all probability, the viral infection was a more important part of the disease than we had assumed.
VIRUS UNDERSTANDING. The pandemic with covid-19 has illustrated that medical science has a way to go when it comes to understanding viral infections. Why do some people get sick and die from the coronavirus, while others barely notice that they are infected? Nor is the development of immunity to the coronavirus understood. Medical science seems to have the same challenges when it comes to understanding enterovirus.
Enterovirus is a viral family that causes serious illness. A book written by the English physician John Richardson describes 7,000 patients with chronic infections caused by enteroviruses. Many of these patients underwent a development in which the viral infection started in the gastrointestinal tract, passed into nearby muscles - and from there found its way into the thoracic spine. There, the virus damaged nerves and muscles, often with the result that patients had pronounced dizziness (labyrinthitis) and wing-leafing. It's like reading my story.
CAUSE OF SEVERAL CONDITIONS? The Enterovirus Foundation (EVF) is a foundation in the United States that works to increase knowledge about enterovirus. Their "Board of Directors" includes several professors and researchers in the field. The foundation points to enterovirus as the cause of a number of diseases and conditions.
Some of these associations are recognized in medical science, such as myocarditis, type 1 diabetes, hand-foot and mouth disease, meningitis and severe chest pain.
EVF also points to studies that suggest that enteroviruses may play a role in diseases that medical science does not understand the cause of, such as ME.
Coxsackievirus is a type of enterovirus with affinity for musculature. It is my claim, and experience, that infection of the muscles of the thoracic spine with this type of virus must be an important cause of somatic tinnitus (tinnitus). This is supported in the literature by case studies and other literature.
Tinnitus is a symptom that is not understood, so here there is an obvious need for more research!
DIAGNOSIS - FIRST CHALLENGE. In order to detect enterovirus, PCR technology is used in Norway - virus RNA is detected in blood and faeces, among other things - something EVF claims is only reliable in acute illness. The EVF claims that the use of PCR leads to false negative test results in more than 70 percent of cases where there is in fact a chronic enterovirus infection. EVF therefore recommends instead the use of immunohistochemistry or serology, which the laboratory in Germany has used for me a number of times. In all cases, the levels of my antibodies have been 6-60 times above what EVF claims are signs of chronic infection. This is met with a shrug by my current doctor, a professor at Rikshospitalet. "We believe in PCR," is the answer from there.
The guidelines for diagnostics in Norway are based on the recommendations of the European Non-polio Enterovirus Network (ENPEN). Der heter det: «Furthermore, there is a high prevalence of EV antibodies in the general population from previous exposure and, thus, serologic testing lacks clinical specificity».
Here, ENPEN chooses to ignore all levels of antibodies because antibodies to enterovirus are common in the population. This is contrary to what EVF writes: «The Micro-neutralization test is a very sensitive, specific test and only 11 enteroviruses, coxsackie B1-6 and echoviruses 6, 7, 9, 11, and 30 can be tested using this method. Titers of 1: 160-320 and higher are good indicators of current infection ».
Does chronic enterovirus infection go under the radar because the Norwegian healthcare system follows ENPEN's recommendations for diagnostics?
THINK OUTSIDE THE BOX! For school medicine, it is obviously very difficult to adjust the map. Any change in the paradigm is made on the basis of evidence, often on the basis of large international, randomized, double-blind clinical trials. This is understandable, but it should be remembered that several major advances in medical science have sprung from findings in individual patients.
In our system, it is clear that findings in individual patients do not lead doctors to take new paths and think new thoughts, even if a connection can be made probable. As in my case: both with literature and a lot of validated blood samples from accredited laboratory. Has the requirement for conformity and arrangement in the ranks become too great? I would argue that this lack of commitment and professional curiosity on the part of the doctors is a betrayal of the patients.
My message is that medical science must now take enterovirus seriously. It is likely that this viral family is a major cause of serious, chronic disease in the population. The message from the Enterovirus Foundation must be verified. If it can be established that PCR does not detect chronic enterovirus infection, other methods must replace PCR as a diagnostic tool. Then we can start discussing how to fight chronic disease caused by this destructive virus family."
