@Rvanson
If a drug is strongly dopaminergic and works on the reward centers of the brain (like cocaine), it does tend to get banned, as it can be open to abuse potential.
However, there are lots of drugs and supplements available that boost the dopamine system: I compiled a list of them in
this post.
Prior to getting ill with ME/CFS, I used the the MAO-B inhibitor
deprenyl (aka: selegiline) a lot, on and off for 20 years. It always gave me a very nice and clean and natural-feeling mood boost, and what's more, I found it boosted creatively and lateral thinking ability (dopamine seems to be linked to creativity).
I am very wary of any drug that has tolerance, addiction and withdrawal problems. I never like the idea of becoming addicted to anything. But I found with deprenyl that you could take it for weeks, and when you stopped, there was no unpleasant come down effects at all. For me, that makes it a good drug. I used to take doses of around 2 mg to 5 mg a day. The younger you are, the less you need. So in my 20s, I'd only take around 2 mg daily.
The mood boosting effects of deprenyl I found kick in after around 12 hours. So a good time to take it is the night before the day you need it to work.
Deprenyl is also taken by the longevity enthusiasts (the anti-aging people who want to live longer by taking life extension drugs and supplements), because in mouse studies, taking daily deprenyl extends mouse lifespan by 40%, if I remember correctly (though that benefit probably does not translate to humans). It's a quite a good neuro-protective compound. See:
Deprenyl: The Forgotten Anti-Aging Pill
Unfortunately for me, after I had a serious chronic organophosphate pesticide poisoning 15 years ago, just prior to developing ME/CFS, deprenyl completely stopped working for me as an antidepressant mood booster. So I can no longer benefit from what was a fantastic antidepressant for me. But I found deprenyl to be a great drug.
I have tried all the antidepressant apart from the MAOI drugs - I don't know why I wasn't ever tried on them but I am not going to start on that now. I think the SSRI drugs have done enough damage to my body and brain!
I think deprenyl (selegiline) is a very benign drug, it's actually good for you in many ways, according to the longevity enthusiasts. Nothing like the rather dubious effects of SSRIs.
A similar drug to deprenyl is
moclobemide, which is an MAO-A inhibitor rather than a MAO-B inhibitor like deprenyl. But it works the same way, in preventing the breakdown of dopamine in the brain, thereby increasing the levels of dopamine.
I don't have much experience with moclobemide, so I can't really comment about it.