Resistant starch first feeds Ruminococcus bromii, which appears to be a keystone species that first breaks down resistant starch into fragments, so that a wider variety of bacteria can ferment it. Bifido does increase, but only if Ruminococcus is also present. Ruminococcus does produce butyrate, but the health effects go far beyond one SCFA or one strain of bacteria. Animal studies are showing that more than 200 genes are turned on or off in the large intestine from resistant starch fermentation. Some of those genes help control digestive function, i.e., muscular contractions in the colon, but some of them are related to metabolism, i.e., GLP-1 and PYY and insulin sensitivity. There's actually a lot going on in the intestinal soup, and researchers are creating new types of super computer analyses to try to figure it out.
The newest one was a diet swap between African Americans living in Pittburgh and South Africans just published in
Nature Communications. This paper makes my head spin with its analysis and graphics! The African Americans ate 39 grams of resistant starch/day (matching the traditional South African consumption) and had significant reductions of mucosal inflammation in the colon cells and colon cancer biomarkers as well as major shifts in the microbiome.
100% agree with JPV that you should start with lower levels of RS and build up, especially if you've got a microbial imbalance or intestinal issues. Most of the studies (like 70+ human clinical studies) are with RS2 from high amylose corn known as Hi-maize. Very few studies have been done in populations with intestinal diseases, although some groups in Australia are beginning to look at it. It's expected to be really complicated because there are so many different variations of microbial imbalances and intestinal disease manifestations. I've seen only one abstract presented at a scientific meeting that fed RS to individuals with intestinal dysfunction, but the full paper isn't yet published. If you want to see the full list of RS clinicals, see
http://www.resistantstarch.us/clinical-research-summary/resistant-starch-clinical-list/. Be prepared, there are 111 of them!