Dr Asad Khan discussing the promising new ‘Apheresis’ treatment for #longcovid on BBC News. He has gone from being in a wheelchair to walking short distances.
IS APHERESIS A CURE/TREATMENT FOR LONG COVID AND ME?
Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin
- Etheresia Pretorius,
- Mare Vlok,
- Chantelle Venter,
- Johannes A. Bezuidenhout,
- Gert Jacobus Laubscher,
- Janami Steenkamp &
- Douglas B. Kell
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by acute clinical pathologies, including various coagulopathies that may be accompanied by hypercoagulation and platelet hyperactivation. Recently, a new COVID-19 phenotype has been noted in patients after they have ostensibly recovered from acute COVID-19 symptoms. This new syndrome is commonly termed Long COVID/Post-Acute Sequelae of COVID-19 (PASC). Here we refer to it as Long COVID/PASC. Lingering symptoms persist for as much as 6 months (or longer) after acute infection, where COVID-19 survivors complain of recurring fatigue or muscle weakness, being out of breath, sleep difficulties, and anxiety or depression. Given that blood clots can block microcapillaries and thereby inhibit oxygen exchange, we here investigate if the lingering symptoms that individuals with Long COVID/PASC manifest might be due to the presence of persistent circulating plasma microclots that are resistant to fibrinolysis.
Inflammatory micro clots in blood of individuals suffering from Long COVID
Date:October 4, 2021Source:Stellenbosch UniversitySummary:Researchers have found an overload of various inflammatory molecules, 'trapped' inside insoluble microscopic blood clots (micro clots), in the blood of individuals suffering from Long COVID.Share:
New research indicates that an overload of various inflammatory molecules, literally "trapped" inside insoluble microscopic blood clots (micro clots), might be the cause of some of the lingering symptoms experienced by individuals with Long COVID.
This unexpected finding was made by Prof Resia Pretorius, a researcher in the Department of Physiological Science at Stellenbosch University (SU), when she started looking at micro clots and their molecular content in blood samples from individuals with Long COVID. The findings have since been peer-reviewed and published in the journal Cardiovascular Diabetology in August 2021.
I recall 30 or so years ago, that 'sticky' blood was suggested as a cause of ME, and blood-thinning treatment was recommended. Then MEResearchUK published papers showing that the endothelium of the vessels are 'severely' damaged.
Note that Long Covid patients have PEM and are now being given a diagnosis of ME.
I know a severe ME patient has just successfully received this treatment.
It is very early days, but maybe the UK clinics now have something to replace GET and CBT.....a real and effective treatment????