Intracortical GABAergic dysfunction in patients with fatigue and dysexecutive syndrome after COVID-19

[pattismith]

Intracortical GABAergic dysfunction in patients with fatigue and dysexecutive syndrome after COVID-19 - ScienceDirect

https://doi.org/10.1016/j.clinph.2021.03.001

Highlights

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First study applying TMS in patients with fatigue and dysexecutive syndrome in the aftermath of COVID-19.
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TMS studies revealed marked impairment of GABAergic intracortical inhibitory circuits within primary motor cortex.
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TMS may serve as diagnostic tool in cognitive disturbances and fatigue in post-COVID-19 patients.