Horizon
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Has anyone tried the supplement Inosine and have any feedback? It is supposed to help "athletic performance" and potentially act as an immunomodulator?
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Has anyone tried the supplement Inosine and have any feedback? It is supposed to help "athletic performance" and potentially act as an immunomodulator?
There were old threads like http://forums.phoenixrising.me/index.php?threads/inosine-reaction.18758/ , but it does seem like it could use an update in 2017.
It's one of the more intriguing substances (owing to its power), but a lot of literature seems to characterize it as immunosuppressive, which seems contrary to a lot of anecdotes. I think the copout explanation was that it had "normalizing" effects, but I failed to understand (effects on NK cells dominate?). One of the doctors must know how it works.
To me only the uric acid effect was familiar (brewer's yeast and sardines).
To me it seems like it keeps infections away since I had no infections when used it (a year now). There are some interesting studies regarding uric acid levels in autoimmune diseases. If I remember correctly Dr Cheney noticed in his testing that uric acid levels where low in most of his ME patients and that seems to be the case in a lot of autoimmune diseases aswell.
Michael Foxs foundations (research in treatment for Parkinsons) have made some studies on inosine. Aparantly it seems like the patients who had higher uric acid levels got less symptoms so therefore they wanted to try inosine.
https://www.michaeljfox.org/foundation/grant-detail.php?grant_id=403
I thought Inosine was used to shift the immune response towards th1, but I found a few sources saying that Inosine inhibits the th1 response and boosts the th2 response. I would steer clear of this one personally.
Anabol Naturals is the brand that most people seem to use.
https://www.amazon.com/Anabol-Naturals-Inosine-960-Capsules/dp/B006HO9XFG