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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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It has nothing to do with the MTHFR gene. The research into those variations only show a connection with increased rate of birth defects. Those variations are also extremely common - if they caused sound hypersensitivity, everyone would have it.Is this a neurological issue or MTHFR mutation?
Misophonia, literally "hatred of sound", is a rarely diagnosed disorder, commonly thought to be of neurological origin, in which negative emotions (anger, fright, hatred, disgust) are triggered by specific sounds. The sounds can be loud or soft. The term was coined by neuroscientist Pawel Jastreboff and biological scientist Margaret Jastreboff and is sometimes referred to as selective sound sensitivity syndrome.
I have noise sensitivity. I assume it is neurological. I wouldn't say I had a phobia. A lot of us have some sort of noise intolerance. Often it depends on what else I am trying to do. I can do my few kitchen chores with ClassicFM in the background. I can also have the radio in the background while I am reading in bed before going to sleep, but I have to stop reading when the announcer speaks between pieces.Does anyone know why some me/cfs sufferers are hypersensitive to noise to the point of developing a phobia to it?
Does anyone know why some me/cfs sufferers are hypersensitive to noise to the point of developing a phobia to it? What can help reduce the sensitivity to noise?
@Thinktank mentioned "misphonia" -- a hatred of sound. There is another technical word that may apply to your situation -- "hyperacusis", which is defined as "a health condition characterized by an increased sensitivity to certain frequency and volume ranges of sound". Perhaps this is what you are dealing with.
At the crack of dawn some knucklehead started up his Harley right outside my motel room and let it idle for 1/2 hour. Too bad no one stole it.
I have a pair of cockatiels, who are not really very loud, especially compared to cockatoos and other larger parrots, but I used to have to wear ear plugs in the morning, when the sound sensitivity was at its worse and they were doing their morning calls.]
At different times in my life I have lived in urban environments, but I could never do that now - the noise would quickly drive me over the edge. . . . . At the crack of dawn some knucklehead started up his Harley right outside my motel room and let it idle for 1/2 hour. Too bad no one stole it. There is a reason why Mainers call people from Massachusetts "Massholes".
My own hypothesis is that the sound sensitivity problems (and probably visual sensitivity problems too) of ME/CFS may come from poor or dysfunctional P50 sensory gating in the brain. Sensory gating is the brain's filter for incoming information from the senses (such as the ears). See this post for more details of my hypothesis.
Hi Hip. Not that I'm disagreeing with you but the P50 component (early pre-conscious response to a stimulus at the approx brainstem level) hasn't really been studied in ME/CFS and I'd like to see it tested with a somatosensory stimulus.
I have to admit that I am not that clued up on the difference between P50 and P300 sensory gating deficit tests. They are very similar though: the tests involve someone listening to two click sounds, separated by 50 and 300 milliseconds respectively.
In healthy people, the brain response (EEG, etc) is reduced for the second click, because there is an automatic sensory desensitization/filtering mechanism in the brain. But for people with sensory gating problems, the brain response to the second clicking sound is not reduced as it should be.
By what you are saying, the longer timescale of 300 milliseconds would seem to capture the desensitization/filtering responses in higher order processes (in the brain cortexes).
Interestingly, quite a few ME/CFS patients seem to have problems focusing on one specific conversation in a loud environment full of other people talking and/or background music: ME/CFS patients can find it difficult to focus on one relevant sound, and mentally filter out the irrelevant sounds.
During the time period described above, we spent every bit of my husband's vacation time looking, across three provinces, for an acreage property we could afford. We soon realized we would have to be multi-millionaires to be able to purchase a piece of land large enough to insulate me from the "Masshole" behaviours of the "oblivious masses".