Well its on topic for me
@MeSci.
My HPA Axis is definitely amiss. I hadn't thought that that might be down to Mito too, but as you say, of course it could. Certainly when I am ill compared to when I am well, I react completely differently to stress, and have seemingly normal levels of stress resistance when I am very well (rare). But repeated stress wears this resistance down quite quickly. It almost seems as if the parasympathetic nervous system doesn't work at all, and I have to suffer all the adrenaline and fear only. Mito dysfunction in the HPA would well be a factor couldn't it!
Interesting what you say about Mito DNA, as I suspect my Mother had a similar issue to me, though we never got near realising or understanding that.
I have to say that every day I feel like I get a step nearer to understanding what is going on in my body. To start with I would think they were massive strides in understanding, and that I would be able to recover straight away. However, it turns out there are 1,000+ factors, which are all interlinked, so its quite a journey.