@Violeta Well! It's nice to know there are people who travel these threads after we've left them and continue to read them thoughtfully.
I hopped onto my Promethease link and input the SLC19A1 gene and came up with G;G with this information "
Solute carrier family 19 (folate transporter), member 1). Cys (A) allele
associated with reduced plasma folate women with GA and AA genotypes had higher red blood cell folate concentrations, not significantly associated with serum folate or homocysteine levels methotrexate (antifolate drug) uptake lowest in individuals with GG genotype than those with GA or AA genotypes."
So, thank you. I have only been borderline low in Folate on the OAT test and haven't been retested lately. However, on a very recent Spectracell test I was well above 'normal' in thiamin, a tad lower in riboflavin, but borderline in biotion and borderline to low in K2.
I do take 1/4 Seeking Health B-Minus each day which doesn't include methyls, add 400mcg or so Folate,2,000mcg B12, add 500-1,000 mcg Biotin (which I had thought was low because of the avidin in the 2 eggs/day I've been eating for years, but maybe not!) and within the last month or so added in 90mcg of K2 as Jarrow's MK-7, which I had done some research on.
I certainly have some difficulty with starches. I thought I'd been gluten-free for about 7 years, but a test from last year--which nobody much paid attention to, we were busy with other things like my oxalates--showed me to have high IgA, the gliadin anti-body, reactive to gluten and, as
@ahmo pointed out to me in a link many other foods that cross-react with gluten issues. So, I've gone on a completely grain-free diet (which includes rice,corn,eggs, chocolate, dairy, potatoes and a few other things) for just over a week now and we shall see. I'm going to start a thread on this issue as I think it's important. My brother-in-law just sent me a link to a podcast that explains some of these issues more deeply.
Meanwhile, I do appreciate this added confirmation of some of my issues.
As to oxalates--I think the issue is muddier than we might think. Supplementing with regular old B6 is fine--as long as you have enough B2 to convert it to its active form p5p. So my months of supplementing only B6 may well have further depleted my already low stores of B2. Which is also very essential in terms of folate metabolism, of course, in its active form FMN.
I'm working on all this now, trying to figure out just what my body is responding to and what not--and as you and many of us know, it isn't easy...!