I can see the merit of this approach, but I also want to know what are the potential harms before starting a treatment. I don't have unlimited funds to spend on herbal medications or other supplements. And that's setting aside any side effects from the treatments themselves that may be harmful.
There are very few ME/CFS treatments that have long-term potential harms; most of the ones that do are major medical interventions.
Off the top of my head, the following carry some risk: IVIG
(sometimes has adverse effects), heavy long-term antibiotics
(for those who think ME/CFS is due to stomach bacteria; or for Lyme), oxymatrine
(can occasionally trigger rheumatoid arthritis in those with autoimmune tendencies), Abilify
(at full doses at least, antipsychotics can substantially increase the risk of type 2 diabetes, and may cause permanent extrapyramidal symptoms), Imunovir
(some people report becoming permanently worse).
Of course, many treatments can have side effects which make you feel worse; but in most cases those side effects disappear as soon as you stop the treatment. In my case, I unfortunately find that lots of treatments worsen my mental health, forcing me to stop them, even though the treatments themselves may have been of major benefit to my ME/CFS, had I been able to follow them through.
Finances are another issue, and it is good to try to come to a judgement beforehand on how likely a treatment is going to work for you, and limit your experiments to treatments where you feel there is some chance of success.
If several ME/CFS patients have benefited from a treatment, then that usually is a good indication that it may be worth trying.