Has anyone ever tried ECULIZUMAB for ME/CFS? Are there patients with concomitant PNH?

[wastwater]

Liver transplant to stop the defective complement destroying the kidney is used in extremely rare severe aHUS (That’s how I understood it) and partial aHUS maybe more common and slower progression

 

[Ladycreole03]

Someone in my Covid Support Group has taken it after IVIG since it has not been successful but Eculizumab has been a godsend. Been 7 weeks, will keep you posted for any updates!

Hi, any updates on that person with ME with this medicine?

 

[Dude]

Accidental discovery: Monoclonal antibody could help with severe virus infections

Scientists from Salzburg have discovered a potential new treatment for severe virus infections in a 38-year-old patient who was simultaneously infected with SARS-CoV-2 and Hantavirus. The patient was treated with a monoclonal antibody Eculizumab that inhibits the complement system. The complement system is a part of the immune system that can become overactivated during a virus infection and can lead to organ damage.

After a single infusion of the antibody, the patient's laboratory values normalized. The doctors believe that the two infections together had exacerbated the patient's kidney problems.

The researchers now want to investigate in further studies whether the antibody is also effective in other severe virus infections.

Source