Waverunner
Senior Member
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The reason why I ask this question is that over the last years a lot of new biologics were approved by the FDA and EMA for different indications. Once the biologic has been approved for one indication pharma companies test its efficacy for other diseases. Many newer biologics are effective for not one but for several diseases.
For example, Risankizumab is one of the most effective - but also expensive - treatments for psoriasis:
https://jamanetwork.com/journals/jamadermatology/fullarticle/2759772
However, Risankizumab also seems to be effective in Crohn's disease and PsA. The same is true for most other biologics in this list, they are approved or were submitted for different immunological diseases.
The specific cause of CFS is still unknown. However, if these new biologics are effective for a wide variety of immunological diseases, they could also be effective for CFS, if CFS has some immunological origin.
Hence, it would be very nice to know if any patient with CFS is benefitting from a specific biologic. We know that rituximab seemed to be beneficial for some patients but rituximab is quite old, it can have some serious side effects and other studies did not show efficacy for CFS.
New research studies for biologics in CFS would be very interesting since we have so many new drugs and fatigue is one major symptom in many immunological diseases.
For example, Risankizumab is one of the most effective - but also expensive - treatments for psoriasis:
https://jamanetwork.com/journals/jamadermatology/fullarticle/2759772

However, Risankizumab also seems to be effective in Crohn's disease and PsA. The same is true for most other biologics in this list, they are approved or were submitted for different immunological diseases.
The specific cause of CFS is still unknown. However, if these new biologics are effective for a wide variety of immunological diseases, they could also be effective for CFS, if CFS has some immunological origin.
Hence, it would be very nice to know if any patient with CFS is benefitting from a specific biologic. We know that rituximab seemed to be beneficial for some patients but rituximab is quite old, it can have some serious side effects and other studies did not show efficacy for CFS.
New research studies for biologics in CFS would be very interesting since we have so many new drugs and fatigue is one major symptom in many immunological diseases.