Fred,
Thanks for the reply. I know that it's all a complex puzzle. Just thought I would ask in case you'd encountered the swollen glands thing in connection to anything in particular. I get that a lot, but it was particularly distinct and particularly bad with the methylation start-up. I've been on the full protocol (including 5000 - 10000 methyl B12, and one Dibencozide daily). Wasn't taking any glutathione, whey, etc. just in case I was one of that group.

Wasn't taking any folic acid, for similar reasons. When I started to get really sick, I decided to put the methylfolate on hold for a while and tackle other things in my program, as I didn't want to build up any bad momentum (I think I got lulled into a false sense of security and increased my dose too quickly, so I wanted to try fresh). Consequently can't say if the symptoms would have passed on their own or not with time. Will give it another try again sometime. Didn't notice any problem with any of the B12's on their own (potassium dropped some, but that was pretty easily corrected as far as I can tell). Just the methylfolate, and previously the SAMe. At the time I started the SAMe, I knew nothing about methylation and wasn't yet diagnosed with ME, so just cut the dose down a lot and rode out the initial side effects and they passed with time.
Thanks again for the help. I didn't expect that you'd necessarily be able to pinpoint the problem for me. Just thought it was worth a try to see.