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Glial activation and natural product

Rufous McKinney

Senior Member
Messages
13,354
Well that sounds interesting! Further perusal suggests its a Chinese herb...., from below I cannot determine if its a Traditional herb.

"Securinine is the major alkaloid natural product from the root of the plant securinega suffruticosa. It was originally discovered over 50 years ago and reported to have potent biological activity [5]. Though this compound has not been utilized in the United States, it has been used clinically in several other countries particularly China and Russia. In China it is considered one of the 50 fundamental Chinese herbs and is used in Chinese herbal medicine [6]."

This would suggest one could get it: at a traditional Chinese Herbalist...(however, the statement it was "discovered" 50 years ago is not consistent with it being in the CTM protocols). Can't check on that at the moment...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123298/
 

Lisa108

Senior Member
Messages
675
The plant securinega suffruticosa is also known as flueggea suffruticosa..
Wiki says this about it:
Flueggea suffruticosa is a species of flowering plant in the family Phyllanthaceae. It is one of the 50 fundamental herbs used in traditional Chinese medicine, where it has the name yī yè qiū (Chinese: ).[2]
Flueggea suffruticosa contains the alkaloid securinine,[citation needed] which has been regarded as a CNS stimulant since the 1960s,[citation needed] and was used to study other related effects on the CNS as a GABAA receptor antagonist in Russia and China.[3][failed verification]
So while the alkaloid securinine has only been known since the 1960's, the herb has been used for longer in TCM.