Leaves don't want to depress you but it was actually about 12 months before I improved after taking the Immunovir, It just kept going on and on, I thought I was never going to improve again but I did, keep on taking what feels right is my advice, I don't do herx, I just stop whatever it is my body is objecting to, maybe I won't ever get better that way I dunno but at least I have some quality of life, I potter about etc etc.