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Game-Changing "Leaky Gut" Treatment (Larazotide Acetate) will soon be available


Senior Member
It's been 5 yrs since @Waverunner posted about this - Mayo Clinic: Is Larazotide Acetate the Answer to Leaky Gut/Celiac Disease?

And it's just now nearing completion, undergoing Phase III trials now.

Larazotide Acetate drastically improves intestinal barrier integrity. It's a zonulin antagonist.

Increased serum zonulin levels are accompanied by a leaky intestinal barrier, dysbiosis and inflammation. Zonulin is a fairly new discovery, and it appears can be used as a biomarker for leaky gut & intestinal permeability testing.

Ref 1. Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis
Ref 2. All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases

John Temperato (9 Meters Biopharma) says...
He expects to perform an interim analysis by mid-2021 and a final analysis at the end of that year. “We want to petition the FDA for conditional approval.” The waiver helps support that.