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FMO3 gene

Messages
15
Location
London, UK
Hi,

Has anyone heard of any research that may implicate the FMO3 gene with CFS/ME?

I have a couple of genetic variations that predispose me to TMAU (fish odour syndrome), but as far as I'm concerned, TMAU is only a symptom of malfunctioning FMO3. My version of TMAU is intermittent and, generally, dependent on stress levels and the food I eat, so it's fairly easy to control. Some people have an extreme version of TMAU which affects them enormously (in a social sense), fortunately I don't, but I do have ME (whatever that turns out to be).

FMO3 plays a big part in the metabolisation of foodstuffs and environmental and endogenous chemical compounds, and, since a lot of people with CFS/ME have problems with chemical sensitivity, drug intolerances and dodgy hormones it seems reasonable to consider FMO3 involvement somewhere along the way.

Anyone have any thoughts, or info, on this?

trace
 

*GG*

senior member
Messages
6,389
Location
Concord, NH
Hi,

Some people have an extreme version of TMAU which affects them enormously (in a social sense), fortunately I don't, but I do have ME (whatever that turns out to be).

trace

Sorry, don't know much about genetics, wish I had studied it in College. What do you mean by "whatever that turns out to be?" I believe ME is well defined.

GG