Fish oil - EPA/DHA ratio

splusholia

Senior Member
Messages
211
Likes
552
Does anybody find a particular ratio helpful for them? I’m looking for something to dampen inflammation. I know some people say we should only have EPA. Do others agree?
 

gbells

Improved ME from 2 to 6
Messages
1,433
Likes
1,802
Location
Eastern NC USA
It would help a little bit but not enough. Hemp oil is better to use than fish oil which is often rancid, more expensive and worse for the environment.
 

Learner1

Senior Member
Messages
6,256
Likes
11,587
Location
Pacific Northwest
I doubt that EPA/DHA ration can do anything noticeable for inflammation...
It would help a little bit but not enough. Hemp oil is better to use than fish oil which is often rancid, more expensive and worse for the environment.
"Fish oil omega-3s EPA and DHA work differently on chronic inflammation: Small randomized trial in older adults compares benefits of the two in supplements -- ScienceDaily" https://www.sciencedaily.com/releases/2020/12/201207091313.htm

"EPA, DHA, and Inflammatory Markers: A Piece of the PUFA Puzzle?" https://www.medscape.com/viewarticle/942767

"Abstract 227: Differential Effects of DHA and EPA Supplementation on Serum Inflammatory Markers and Blood Monocyte Inflammatory Response in Subjects with Chronic Inflammation | Arteriosclerosis, Thrombosis, and Vascular Biology" https://www.ahajournals.org/doi/10.1161/atvb.39.suppl_1.227

"Omega-3 Fatty Acids in Rheumatic Diseases: A Critical Review : JCR: Journal of Clinical Rheumatology" https://journals.lww.com/jclinrheum...3_Fatty_Acids_in_Rheumatic_Diseases__A.6.aspx


This is also an interesting product:

"SPM Active® | Metagenics, Inc." https://www.metagenics.com/spm-active
 

Pyrrhus

Senior Member
Messages
4,032
Likes
12,323
Location
U.S., Earth
Minami Nutrition, who use an extraction process without any heat, to fully preserve the Omega-3 from fish oils, recommends a ratio of 756 mg EPA to 228 mg DHA for *healthy* people:
https://pubmed.ncbi.nlm.nih.gov/23924406/

But personally, I can't tolerate DHA, only EPA.

Personally, I found Minami's pure 500mg EPA product superior to Vascepa's synthetic prescription 1000mg EPA, for cognitive benefits. (not sure why they're so different)

There do seem to be significant problems with the quality of most fish oil supplements, and one possible reason is that these oils may degrade rapidly with exposure to oxygen or heat.

I don’t like to endorse specific brands, but I have been impressed with the quality of Minami brand omega-3 products. They don’t use any heat in the processing of their products, which may be one of the reasons for the high quality. In the U.S., these products are distributed by a company called Garden of Life. They are expensive, though.
 
Last edited:

splusholia

Senior Member
Messages
211
Likes
552
"Fish oil omega-3s EPA and DHA work differently on chronic inflammation: Small randomized trial in older adults compares benefits of the two in supplements -- ScienceDaily" https://www.sciencedaily.com/releases/2020/12/201207091313.htm

"EPA, DHA, and Inflammatory Markers: A Piece of the PUFA Puzzle?" https://www.medscape.com/viewarticle/942767

"Abstract 227: Differential Effects of DHA and EPA Supplementation on Serum Inflammatory Markers and Blood Monocyte Inflammatory Response in Subjects with Chronic Inflammation | Arteriosclerosis, Thrombosis, and Vascular Biology" https://www.ahajournals.org/doi/10.1161/atvb.39.suppl_1.227

"Omega-3 Fatty Acids in Rheumatic Diseases: A Critical Review : JCR: Journal of Clinical Rheumatology" https://journals.lww.com/jclinrheum...3_Fatty_Acids_in_Rheumatic_Diseases__A.6.aspx


This is also an interesting product:

"SPM Active® | Metagenics, Inc." https://www.metagenics.com/spm-active
Oh, I’d like to try that! The reviews are interesting. Doesn’t look like it’s available in the U.K. though.