@Hanna
Exactly right. In my opinion our bodies can be affected towards CFS/ME mainly from (list not inclusive) :
a) Infection
b) Medication
c) After a surgery
d) Psychological Stress
It is great that people with Post-Accutane syndrome and Post-finasteride syndrome begin thinking there is a link here as many of their symptoms resemble those of CFS/ME.
Note that (a) and (b) most likely go hand in hand and the same holds for (b)+(c) so as you understand the Liver is stressed even more because you have two factors that overload our detox system (Virus + Medication). A good question would be : whether people who got CFS/ME after a surgery, actually got it after the medication that was given prior and after the surgery (?)
All of these factors (Viruses + medications) generate Oxidative stress and then Endoplasmic Reticulum stress and then the Unfolded Protein Response.
http://algogenomics.blogspot.com/2017/08/dili-viruses-and-er-stress.html
Please see the chart here and see how many Topics you heard before : Mitochondria, Cytokines, Inflammation, Innate Immune System, B and T Cells :
http://forums.phoenixrising.me/inde...sted-research-on-cfs.51283/page-5#post-890015