Enterovirus 71 (EV71) in 97% of ME/CFS?

sometexan84

sometexan84

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@Pyrrhus Did you already talk about this somewhere? If so, I can move this thread to a more appropriate place..

So, there was a Twitter mention not long ago regarding Dr. Chia finding 97% of ME/CFS having this unknown enterovirus protein in the blood, labeled merely as a "53k enteroviral protein". Earlier, I THINK I found what that might be...

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Enterovirus 71 or Enterovirus A71 https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006778
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http://sourcedb.shanghaipasteur.cas.cn/zw/lwk/201103/P020110324600357435200.pdf
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EV 71 has (to my knowledge) never been implicated in ME/CFS and here's a new article (Feb 2022)... Enterovirus 71 Antagonizes Antiviral Effects of Type III Interferon and Evades the Clearance of Intestinal Intraepithelial Lymphocytes https://www.frontiersin.org/articles/10.3389/fmicb.2021.806084/full
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Basically, it's very much reiterating stuff we'd already discovered in the other studies, w/ enterovirus shutting down our interferon. And that Type III IFN lambda appears to be extremely effective.

However, an EV 71 or even EV D68... I mean, these enteros have again NOT been implicated in ME/CFS and it's looking more and more like they could be VERY much involved... so not just Coxsackie B and Echovirus.

The Twitter comment is just by a single person and is second-hand info.. so take w/ a grain of salt. Still, interesting that the other EVs are perhaps starting to come into play.
 
Judee

Judee

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Pearshaped said:
jodi Basset‘s hfme.org
Click to expand...

Hey, @Pearshaped, I can't find on there where Jodi she mentions EV 68-71. I did see her mention of entroviruses though. Would you be able to link that page for me if you have a chance?

sometexan84 said:
And that Type III IFN lambda appears to be extremely effective.
Click to expand...

I've forgotten @sometexan84. Did you say if your group was able to get that and start it? I think the last thing I saw you post about a time line was February. Sorry if I missed an update.
 
sometexan84

sometexan84

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Pearshaped said:
@sometexan84
EV 68 -71 are closely linked to ME.

Look at Byron Hyde‘s work or jodi Basset‘s hfme.org
Click to expand...
Well yes, but there are still many who don't agree. And it's not been largely discussed like Coxsackie B and Echo.

However, I think this is about the change. And yea, EV D68 is another I'm very suspicious of.
 
sometexan84

sometexan84

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Judee said:
I've forgotten @sometexan84. Did you say if your group was able to get that and start it? I think the last thing I saw you post about a time line was February. Sorry if I missed an update.
Click to expand...
Yea, so we've actually had multiple setbacks unfortunately, and have not yet started. It's still being tested in 3rd party labs for verification/authentication and quality.

If I had to guess, I'd say April is when the group will actually begin the treatment.

That said, I do plan on posting more here in the PR forum about this treatment and the latest enterovirus research to try and update everyone
 
sometexan84

sometexan84

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Judee said:
Let us know if you can.
Click to expand...
I'm going to try and start doing a better job of updating everyone here in PR w/ everything. I've been kind of distracted. But yea, there's actually lots of good news and solid research lately that I really would like to share and just be more proactive about posting here to everyone.

The second I start the treatment, I promise the updates will come rolling in... from myself, and likely from the others who are following in my footsteps.
 
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Pearshaped

Pearshaped

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sometexan84 said:
Well yes, but there are still many who don't agree. And it's not been largely discussed like Coxsackie B and Echo.

However, I think this is about the change. And yea, EV D68 is another I'm very suspicious of.
Click to expand...


Here a quote from E. Dowsett :
https://www.hfme.org/researchviral.htm
„Myalgic
encephalomyelitis and other chronic neurological and
motor neurone conditions, caused by a wide range of non
polio enteroviruses (Coxsackie, ECHO and enterviruses
68-71)“..

encephalomyelitis from EV 71 https://pubmed.ncbi.nlm.nih.gov/21861081/

Hyde mentions a patient who got ME after EV 71:
https://www.nightingale.ca/_files/ugd/5b307e_1f2ab80503974be084d77d6070efbd3a.pdf

this is just a case report EV 68 but nonetheless:
https://pubmed.ncbi.nlm.nih.gov/28819079/


Tbh I came across it several times so I was convinced it was better researched, but Coxsackie and Echo are obviously closer linked to ME.

There is a guy on twitter who got ME after EV 71.

[My journey began with EV 70 but was followed from other infections, so dont know which one caused the most harm.]
Edit: typo, actually it was EV 72 but that is not really linked to ME.
 
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sometexan84

sometexan84

Senior Member
Messages
1,241
Pearshaped said:
Here a quote from E. Dowsett :
https://www.hfme.org/researchviral.htm
„Myalgic
encephalomyelitis and other chronic neurological and
motor neurone conditions, caused by a wide range of non
polio enteroviruses (Coxsackie, ECHO and enterviruses
68-71)“..

encephalomyelitis from EV 71 https://pubmed.ncbi.nlm.nih.gov/21861081/

Hyde mentions a patient who got ME after EV 71:
https://www.nightingale.ca/_files/ugd/5b307e_1f2ab80503974be084d77d6070efbd3a.pdf

this is just a case report EV 68 but nonetheless:
https://pubmed.ncbi.nlm.nih.gov/28819079/


Tbh I came across it several times so I was convinced it was better researched, but Coxsackie and Echo are obviously closer linked to ME.

There is a guy on twitter who got ME after EV 71.

[My journey began with EV 70 but was followed from other infections, so dont know which one caused the most harm.]
Edit: typo, actually it was EV 72 but that is not really linked to ME.
Click to expand...
Do you have a link to the guy on twitter ?
 
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