My last focus in finding an effective treatment is on viruses.
I'm honestly extremely confused whether the viruses are active in my case or not (the uncertainty is in EBV and VZV). According to some criteria yes, according to others no. Difficult to judge also in connection with my strangely functioning immunity.
I'm based on 16 times higher titers mentioned in
@Hip roadmap and also from some studies which
@Learner1 sent me. And for sure I also tried to find Lerner and Montoya criteria.
I also mentioned it in the
@Pyrrhus thread about antivirals, but I don't want to spam him there about reading the results.
So…
I decided to try Valacyclovir (1g 3x day) for 6 months + many antiviral herbs.
I tolerated it well, no side effects, liver tests perfectly fine. But this antiviral treatment did nothing for me.
See also the comparison of results before and after treatment:
10-2021
EBNA IgG 12.56 >> S/CO (0.00 - 0.50)
EBV VCA IgG 67.30 >> S/CO (0.00 - 0.75)
EBV VCA IgM 0.05 S/CO (0.00 - 0.50)
EBV EA IgG <5 U/mL (0 - 40)
4-2022
EBNA IgG 12.32 >> S/CO (0.00 - 0.50)
EBV VCA IgG 52.42 >> S/CO (0.00 - 0.75)
EBV VCA IgM 0.03 S/CO (0.00 - 0.50)
EBV EA IgG 5 U/mL (0 - 40)
*EBV blood PCR is always negative, but saliva PCR was high! Not I'm waiting for new result from re-test.
10-2021
VZV IgA 0.06 IP (0.00 - 0.90)
VZV IgG 3.87 >> IP (0.00 - 0.90)
VZV IgM 0.10 IP (0.00 - 0.90)
4-2022
VZV IgM 0.20 IP (0.00 - 0.99)
VZV IgG 1998.0 >> IU/L (0.0 - 150.0)
VZV IgA 0.11 IP (0.00 - 0.90)
*VZV blood PCR is always negative
Valtrex is either very ineffective or I really don't have a problem with these viruses.
But what worried me so much in recent blood tests is the idea of whether my antibodies are real and adequate, because my immunologist said I have "
Polyclonal activation of the immune system".
She told me this based on antibody results after the
3rd covid vaccine (what makes me worse).
Look at the extreme result!
SARS-CoV-2 IgG S1 62505.1 >> AU/ml (0 – 14)
If I understand this well, it can be a clear indicator of my immune system is overactive / chronic active and it may be a sign of autoimmunity and it is necessary to calm him down.
I would like to discuss it, because "polyclonal activation of the immune system" is new is a new term for me.
I found in Google search rather "
Polyclonal B cell response" - I need to find out more.
These are all possible reasons to try
Rapamycin and
Pentoxifylline. Maybe…
Now the immunologist has given me a short "shoot" of
Methylprednisolone (Medrol) to calm my immunity, but I only managed it for a day, because it exhausted me and I felt like it was burning from the inside. The feeling of strong inflammation increased, so did the heat intolarance, perhaps it quickly subsides after discontinuation. Has anyone encountered this with these corticosteroids? It weird, because the effect should be the exact opposite!