I have Celiac. <waves frantically> I came up hetero AC as well on this test. There are 22 or 23 genes associated with Celiac though. 23andme only tests one.
roxie60 the 20 - 30% false negative your neurologist quoted is probably about right. Doctor's love to only test Igg or IgA antibodies. Then they don't check to see if the IgA is low. If it's low already you'll get a false negative. My doc only checked Igg. I didn't have the antibodies. I was diagnosed through endoscopy (found villous atrophy) and positive response to gluten free diet. Doctors need to do a FULL Celiac panel to rule out the disease and that is far too often not done.
Also Celiac is genetic, but it's triggered. So if you have the gene, but it hasn't been triggered yet, you're not making antibodies. If you're not making the antibodies it won't show up on blood work.
That's my quick lesson on Celiac. There's also NCGI (non celiac gluten intolerant) and fun stuff like gluten ataxia. Hope that's all clear as mud.
