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JAX ME/CFS CRC Scientific Progress – 2019
On July 12, 2019 By jaxmecfs
Research in the ME/CFS field has implicated immune and microbial dysbiosis in ME/CFS patients, so a major goal of our ME/CFS Center at JAX is to deeply characterize patient clinical phenotypes together with immunologic, metabolic, and microbiome markers in the blood and gut. Over the course of the five year study, we aim to recruit 150 ME/CFS patients and follow them through three time points over the course of three years, where we will collect detailed clinical information, blood, and stool samples. We also aim to recruit 100 age- and sex-matched healthy controls, and 50 controls will be followed through a second time point. As we approach the end of second year of the study, we would like to share some of our progress with the ME/CFS community.
All of the patient recruitment is done at The Bateman Horne Center of Excellence (BHC), which serves as the Clinical Core for the JAX CRC. We began enrolling our first patients early last year. Since then, our clinical core has done a herculean effort to enroll a total of 131 ME/CFS subjects and 72 healthy controls for this study. The ME/CFS patients have also been divided into two groups: half with disease duration of less than 4 years and the other half for more than 10 years, as we will also be asking how the chronic state of the disease impacts the immunological and metabolic features. We believe that this will be one of the largest of such cohorts for this type of study. We have also started to collect second year time points for subjects who were recruited last year, and so far have had 16 ME/CFS patients and 9 healthy controls come back for biological sample collection and clinical information.
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continues at this link: https://jaxmecfs.com/2019/07/12/jax-crc-study-progress/
On July 12, 2019 By jaxmecfs
Research in the ME/CFS field has implicated immune and microbial dysbiosis in ME/CFS patients, so a major goal of our ME/CFS Center at JAX is to deeply characterize patient clinical phenotypes together with immunologic, metabolic, and microbiome markers in the blood and gut. Over the course of the five year study, we aim to recruit 150 ME/CFS patients and follow them through three time points over the course of three years, where we will collect detailed clinical information, blood, and stool samples. We also aim to recruit 100 age- and sex-matched healthy controls, and 50 controls will be followed through a second time point. As we approach the end of second year of the study, we would like to share some of our progress with the ME/CFS community.
All of the patient recruitment is done at The Bateman Horne Center of Excellence (BHC), which serves as the Clinical Core for the JAX CRC. We began enrolling our first patients early last year. Since then, our clinical core has done a herculean effort to enroll a total of 131 ME/CFS subjects and 72 healthy controls for this study. The ME/CFS patients have also been divided into two groups: half with disease duration of less than 4 years and the other half for more than 10 years, as we will also be asking how the chronic state of the disease impacts the immunological and metabolic features. We believe that this will be one of the largest of such cohorts for this type of study. We have also started to collect second year time points for subjects who were recruited last year, and so far have had 16 ME/CFS patients and 9 healthy controls come back for biological sample collection and clinical information.
...
continues at this link: https://jaxmecfs.com/2019/07/12/jax-crc-study-progress/
