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ME/CFS since 1995; activity level 6?
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Following on from the California outbreak, here is a paper on one in Colorado.
A cluster of acute flaccid paralysis and cranial nerve dysfunction temporally associated with an outbreak of enterovirus D68 in children in Colorado, USA
There is an interesting associated Physician's First Watch article
A cluster of acute flaccid paralysis and cranial nerve dysfunction temporally associated with an outbreak of enterovirus D68 in children in Colorado, USA
There is an interesting associated Physician's First Watch article
Enterovirus D68 May Have Caused Colorado's Cluster of Muscular Weakness
By Joe Elia
Edited by
- Susan Sadoughi, MD, and
- Richard Saitz, MD, MPH, FACP, FASAM
The circumstances surrounding a case cluster of acute flaccid paralysis or cranial nerve dysfunction point to, but do not definitively link it with, enterovirus D68, according to a study in The Lancet.
The cluster comprised 12 Colorado children stricken between August and October 2014. All had gray-matter or brainstem lesions on imaging, and most were febrile at the onset of neurologic symptoms. However, all cerebrospinal fluid specimens were negative for enterovirus. Treatment with antivirals and other agents brought no improvement, and all children with limb weakness showed residual deficits.
What's suggestive is that the cases all occurred during a community-wide outbreak of D68 respiratory illness and that all cases in the cluster had a preceding febrile illness.
A commentary points out that the inability to find D68 in cerebrospinal fluid doesn't necessarily absolve the virus, since similar-acting viruses are more often recovered from stool or throat swabs.
Link(s):
Lancet article (Free abstract) http://click.jwatch.org/cts/click?q=227;68132557;8zhhx2LKxTPJdZdefVYij2W7OkCfBf4O+PkTxgBLDz4=
Background: Physician's First Watch coverage of EV-D68 (Free) http://click.jwatch.org/cts/click?q=227;68132557;8zhhx2LKxTPJdZdefVYij4DoeAz8aEjg+PkTxgBLDz4=