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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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Chromium picolinate for depression while undermethylated?

Hi I want to try out chromium picolinate or polynicotinate for depression. However I have undermethylation and CFS. Has anyone tried these supplements being undermethylated and has it worked for you? any other suggestions?