So I have been taking choline bi tartrate for 10 days today. For the first 8 days i took 20-25 grams a day in divided doses until a few nights ago when I threw up like crazy for hours, and have since lowered the dose to 15 grams a day. I think I have a genetic choline transport defect but will know for sure when I get WGS results back. Acetylcholine plays a role in peristalsis so replenishing that too quick could explain the throwing up. Choline bi tatrate is only 40% choline by weight. I have ordered some choline chloride from overseas which is 75% choline by weight, and will begin taking that once it arrives, and see how the taste, and ease of drinking compares to bi tartrate. They used the chloride forms in the early studies on choline; they gave up to 32 grams a day to schizophrenic, movement disorders, and some other types of patients. Other salts of choline are: choline citrate - 35% choline, and choline bi carbonate -around 63% choline.