CFI Spinal Fluid study from Lipkin and Hornig is out.

[Undisclosed]

Please note:

The posts starting at post 306 and ending with 319 were originally in the thread titled 'New Hornig/Lipkin paper in Molecular Psychiatry'. The posts were merged into this thread as they both are about the same study.

Thank you.

 

[halcyon]

"Our results indicate a markedly disturbed immune signature in the cerebrospinal fluid of cases that is consistent with immune activation in the central nervous system, and a shift toward an allergic or T helper type-2 pattern associated with autoimmunity." - Sexy.

They left room on the table for both hypothesis.

Although increased CSF CCL11 and CXCL10 levels in ME/CFS subjects, along with dysregulation of IL1 signaling, suggest the possibility of an allergic process in central compartments,49,50 such patterns may also be seen in a wide range of CNS infections.

 

[wastwater]

I saw an article on eosinophils t cells and il-2 and il-15,not sure if this is relevant or of interest but here it is
http://www.nejm.org/doi/full/10.1056/NEJM200005253422104
Extra idea : Lame T cells leading to lots of IL-2,to get the t cells working,under viral load.
The side effects of il-2 could explain the symptoms of ME/cfs I always wondered